Synthetic Lethal Mutations
"Synthetic Lethal Mutations" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Mutations in genes which lead to cell or organism death when occurring in combination with mutations in one or more other genes.
| Descriptor ID |
D000072020
|
| MeSH Number(s) |
G05.365.590.917
|
| Concept/Terms |
Synthetic Lethal Mutations- Synthetic Lethal Mutations
- Synthetic Lethal Mutation
- Lethal Mutation, Synthetic
- Lethal Mutations, Synthetic
- Mutation, Synthetic Lethal
- Mutations, Synthetic Lethal
|
Below are MeSH descriptors whose meaning is more general than "Synthetic Lethal Mutations".
Below are MeSH descriptors whose meaning is more specific than "Synthetic Lethal Mutations".
This graph shows the total number of publications written about "Synthetic Lethal Mutations" by people in this website by year, and whether "Synthetic Lethal Mutations" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Synthetic Lethal Mutations" by people in Profiles.
-
Allele-specific suppression in Caenorhabditis elegans reveals details of EMS mutagenesis and a possible moonlighting interaction between the vesicular acetylcholine transporter and ERD2 receptors. Genetics. 2021 08 09; 218(4).
-
XRN2 interactome reveals its synthetic lethal relationship with PARP1 inhibition. Sci Rep. 2020 08 28; 10(1):14253.
-
PARP inhibitors in castration-resistant prostate cancer. Cancer Treat Res Commun. 2020; 24:100199.
-
Kub5-Hera RPRD1B Deficiency Promotes "BRCAness" and Vulnerability to PARP Inhibition in BRCA-proficient Breast Cancers. Clin Cancer Res. 2018 12 15; 24(24):6459-6470.