"Founder Effect" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phenomenon that is observed when a small subgroup of a larger POPULATION establishes itself as a separate and isolated entity. The subgroup's GENE POOL carries only a fraction of the genetic diversity of the parental population resulting in an increased frequency of certain diseases in the subgroup, especially those diseases known to be autosomal recessive.
| Descriptor ID |
D018703
|
| MeSH Number(s) |
G05.285
|
| Concept/Terms |
Founder Effect- Founder Effect
- Effect, Founder
- Effects, Founder
- Founder Effects
|
Below are MeSH descriptors whose meaning is more general than "Founder Effect".
Below are MeSH descriptors whose meaning is more specific than "Founder Effect".
This graph shows the total number of publications written about "Founder Effect" by people in this website by year, and whether "Founder Effect" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2016 | 1 | 2 | 3 |
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Below are the most recent publications written about "Founder Effect" by people in Profiles.
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Response to Maja Rupnik. Anaerobe. 2016 Dec; 42:206.
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A novel mouse model for the identification of thioredoxin-1 protein interactions. Free Radic Biol Med. 2016 10; 99:533-543.
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Reclassification of Clostridium difficile as Clostridioides difficile (Hall and O'Toole 1935) Prévot 1938. Anaerobe. 2016 Aug; 40:95-9.
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Founder effect for the Ala431Glu mutation of the presenilin 1 gene causing early-onset Alzheimer's disease in Mexican families. Neurogenetics. 2006 Jul; 7(3):195-200.
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Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus. Am J Hum Genet. 2002 Sep; 71(3):543-53.
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Molecular biogeography of clonal lineages in a high-arctic apomictic Daphnia complex. Mol Ecol. 1994 Oct; 3(5):497-506.