Receptors, Polymeric Immunoglobulin
"Receptors, Polymeric Immunoglobulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
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Specialized Fc receptors (RECEPTORS, FC) for polymeric immunoglobulins, which mediate transcytosis of polymeric IMMUNOGLOBULIN A and IMMUNOGLOBULIN M into external secretions. They are found on the surfaces of epithelial cells and hepatocytes. After binding to IMMUNOGLOBULIN A, the receptor-ligand complex undergoes endocytosis, transport by vesicle, and secretion into the lumen by exocytosis. Before release, the part of the receptor (SECRETORY COMPONENT) that is bound to IMMUNOGLOBULIN A is proteolytically cleaved from its transmembrane tail. (From Rosen et al., The Dictionary of Immunology, 1989)
| Descriptor ID |
D019056
|
| MeSH Number(s) |
D12.776.543.750.705.871.700
|
| Concept/Terms |
Receptors, Polymeric Immunoglobulin- Receptors, Polymeric Immunoglobulin
- Polymeric Immunoglobulin Receptors
- Immunoglobulin Receptors, Polymeric
- Receptor, Polyimmunoglobulin
- Receptor, Polymeric Ig
- Poly-Ig Receptor
- Poly Ig Receptor
- Receptor, Poly-Ig
- Polyimmunoglobulin Receptor
- Polymeric Immunoglobulin Receptor
- Immunoglobulin Receptor, Polymeric
- Receptor, Polymeric Immunoglobulin
- Polymeric Ig Receptor
- Ig Receptor, Polymeric
|
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