Brain-Derived Neurotrophic Factor
"Brain-Derived Neurotrophic Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the nerve growth factor family of trophic factors. In the brain BDNF has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. (From Kendrew, The Encyclopedia of Molecular Biology, 1994)
| Descriptor ID |
D019208
|
| MeSH Number(s) |
D12.644.276.860.100 D12.776.467.860.100 D12.776.631.600.100 D23.529.850.100
|
| Concept/Terms |
Brain-Derived Neurotrophic Factor- Brain-Derived Neurotrophic Factor
- Brain Derived Neurotrophic Factor
- Factor, Brain-Derived Neurotrophic
- Neurotrophic Factor, Brain-Derived
- BDNF
|
Below are MeSH descriptors whose meaning is more general than "Brain-Derived Neurotrophic Factor".
Below are MeSH descriptors whose meaning is more specific than "Brain-Derived Neurotrophic Factor".
This graph shows the total number of publications written about "Brain-Derived Neurotrophic Factor" by people in this website by year, and whether "Brain-Derived Neurotrophic Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Brain-Derived Neurotrophic Factor" by people in Profiles.
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Brain-Derived Neurotrophic Factor in Retinal Integrity Under Diabetic and Hypoxic Conditions. Adv Exp Med Biol. 2025; 1468:293-296.
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Muscle-generated BDNF (brain derived neurotrophic factor) maintains mitochondrial quality control in female mice. Autophagy. 2022 06; 18(6):1367-1384.
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VEGF Mediates Retinal Müller Cell Viability and Neuroprotection through BDNF in Diabetes. Biomolecules. 2021 05 10; 11(5).
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Muscle-generated BDNF is a sexually dimorphic myokine that controls metabolic flexibility. Sci Signal. 2019 08 13; 12(594).
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Dysregulation of the SNARE-binding protein Munc18-1 impairs BDNF secretion and synaptic neurotransmission: a novel interventional target to protect the aging brain. Geroscience. 2019 04; 41(2):109-123.
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BDNF mimetic alleviates body weight gain in obese mice by enhancing mitochondrial biogenesis in skeletal muscle. Metabolism. 2018 10; 87:113-122.
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Plantar stimulation in parkinsonians: From biomarkers to mobility - randomized-controlled trial. Restor Neurol Neurosci. 2018; 36(2):195-205.
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Insights into neuroepigenetics through human histone deacetylase PET imaging. Sci Transl Med. 2016 08 10; 8(351):351ra106.
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Neurotrophic growth factor responses to lower body resistance training in older adults. Appl Physiol Nutr Metab. 2016 Mar; 41(3):315-23.
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Hemorrhagic shock-induced cerebral bioenergetic imbalance is corrected by pharmacologic treatment with EF24 in a rat model. Neuropharmacology. 2015 Dec; 99:318-27.