"Nerve Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
NERVE GROWTH FACTOR is the first of a series of neurotrophic factors that were found to influence the growth and differentiation of sympathetic and sensory neurons. It is comprised of alpha, beta, and gamma subunits. The beta subunit is responsible for its growth stimulating activity.
| Descriptor ID |
D020932
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| MeSH Number(s) |
D12.644.276.860.437 D12.776.467.860.437 D12.776.631.600.437 D23.529.850.437
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nerve Growth Factor".
Below are MeSH descriptors whose meaning is more specific than "Nerve Growth Factor".
This graph shows the total number of publications written about "Nerve Growth Factor" by people in this website by year, and whether "Nerve Growth Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 2 | 3 |
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Below are the most recent publications written about "Nerve Growth Factor" by people in Profiles.
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Hemorrhagic shock-induced cerebral bioenergetic imbalance is corrected by pharmacologic treatment with EF24 in a rat model. Neuropharmacology. 2015 Dec; 99:318-27.
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The brain metabolic activity after resuscitation with liposome-encapsulated hemoglobin in a rat model of hypovolemic shock. J Cereb Blood Flow Metab. 2015 Sep; 35(9):1528-36.
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Differential effects of overexpression of Rab5 and Rab22 on autophagy in PC12 cells with or without NGF. Methods Mol Biol. 2015; 1298:295-304.
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Biogenesis and function of the NGF/TrkA signaling endosome. Int Rev Cell Mol Biol. 2015; 314:239-57.
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Paradoxical effect of TrkA inhibition in Alzheimer's disease models. J Alzheimers Dis. 2014; 40(3):605-617.
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Rab22 controls NGF signaling and neurite outgrowth in PC12 cells. Mol Biol Cell. 2011 Oct; 22(20):3853-60.
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Regulation of neurite outgrowth by interactions between the scaffolding protein, JNK-associated leucine zipper protein, and neuronal growth-associated protein superior cervical ganglia clone 10. J Biol Chem. 2010 Feb 05; 285(6):3548-3553.
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Nerve growth factor-mediated neurite outgrowth via regulation of Rab5. Mol Biol Cell. 2007 Apr; 18(4):1375-84.
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C3a enhances nerve growth factor-induced NFAT activation and chemokine production in a human mast cell line, HMC-1. J Immunol. 2004 Jun 01; 172(11):6961-8.