Myogenic Regulatory Factors
"Myogenic Regulatory Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of muscle-specific transcription factors which bind to DNA in control regions and thus regulate myogenesis. All members of this family contain a conserved helix-loop-helix motif which is homologous to the myc family proteins. These factors are only found in skeletal muscle. Members include the myoD protein (MYOD PROTEIN); MYOGENIN; myf-5, and myf-6 (also called MRF4 or herculin).
Descriptor ID |
D018006
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MeSH Number(s) |
D12.776.210.500.570 D12.776.260.103.750 D12.776.930.125.750
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Myogenic Regulatory Factors".
Below are MeSH descriptors whose meaning is more specific than "Myogenic Regulatory Factors".
This graph shows the total number of publications written about "Myogenic Regulatory Factors" by people in this website by year, and whether "Myogenic Regulatory Factors" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 1 | 1 | 2 |
2005 | 3 | 0 | 3 |
2006 | 1 | 0 | 1 |
2008 | 1 | 0 | 1 |
2009 | 0 | 1 | 1 |
2020 | 2 | 0 | 2 |
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Below are the most recent publications written about "Myogenic Regulatory Factors" by people in Profiles.
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Opposite Roles of the JMJD1A Interaction Partners MDFI and MDFIC in Colorectal Cancer. Sci Rep. 2020 05 26; 10(1):8710.
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Inhibitor of myogenic differentiation family isoform a, a new positive regulator of fibronectin production by glomerular mesangial cells. Am J Physiol Renal Physiol. 2020 03 01; 318(3):F673-F682.
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Regulation of GLUT4 expression in denervated skeletal muscle. Am J Physiol Regul Integr Comp Physiol. 2009 Jun; 296(6):R1820-8.
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GLUT4 enhancer factor (GEF) interacts with MEF2A and HDAC5 to regulate the GLUT4 promoter in adipocytes. J Biol Chem. 2008 Mar 21; 283(12):7429-37.
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Hyperphosphorylation of MEF2A in primary adipocytes correlates with downregulation of human GLUT4 gene promoter activity. Am J Physiol Endocrinol Metab. 2007 Apr; 292(4):E1149-56.
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Exercise increases MEF2- and GEF DNA-binding activity in human skeletal muscle. FASEB J. 2006 Feb; 20(2):348-9.
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Beta-catenin regulates myogenesis by relieving I-mfa-mediated suppression of myogenic regulatory factors in P19 cells. Proc Natl Acad Sci U S A. 2005 Nov 29; 102(48):17378-83.
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Regulation of muscle GLUT4 enhancer factor and myocyte enhancer factor 2 by AMP-activated protein kinase. Am J Physiol Endocrinol Metab. 2005 Dec; 289(6):E1071-6.
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Regulation of the human GLUT4 gene promoter: interaction between a transcriptional activator and myocyte enhancer factor 2A. Proc Natl Acad Sci U S A. 2003 Dec 09; 100(25):14725-30.
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Inhibitor of myogenic family, a novel suppressor of store-operated currents through an interaction with TRPC1. J Biol Chem. 2003 Dec 26; 278(52):52763-72.