"rac1 GTP-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A rac GTP-binding protein involved in regulating actin filaments at the plasma membrane. It controls the development of filopodia and lamellipodia in cells and thereby influences cellular motility and adhesion. It is also involved in activation of NADPH OXIDASES. This enzyme was formerly listed as EC 3.6.1.47.
| Descriptor ID |
D020830
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| MeSH Number(s) |
D08.811.277.040.330.300.400.700.100.500 D12.644.360.525.700.100.100 D12.776.157.325.515.700.100.100 D12.776.476.525.700.100.100
|
| Concept/Terms |
rac1 GTP-Binding Protein- rac1 GTP-Binding Protein
- GTP-Binding Protein, rac1
- rac1 GTP Binding Protein
- rac1 Protein
- TC-25 GTP-Binding Protein
- GTP-Binding Protein, TC-25
- TC 25 GTP Binding Protein
- ras-Related C3 Botulinum Toxin Substrate 1
- ras Related C3 Botulinum Toxin Substrate 1
|
Below are MeSH descriptors whose meaning is more general than "rac1 GTP-Binding Protein".
Below are MeSH descriptors whose meaning is more specific than "rac1 GTP-Binding Protein".
This graph shows the total number of publications written about "rac1 GTP-Binding Protein" by people in this website by year, and whether "rac1 GTP-Binding Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 3 | 3 |
| 2011 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 2 | 2 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "rac1 GTP-Binding Protein" by people in Profiles.
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Down-regulation of placental Cdc42 and Rac1 links mTORC2 inhibition to decreased trophoblast amino acid transport in human intrauterine growth restriction. Clin Sci (Lond). 2020 01 17; 134(1):53-70.
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Increased flux through the mevalonate pathway mediates fibrotic repair without injury. J Clin Invest. 2019 11 01; 129(11):4962-4978.
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Sphingosine Kinase-1 Is Essential for Maintaining External/Outer Limiting Membrane and Associated Adherens Junctions in the Aging Retina. Mol Neurobiol. 2019 Oct; 56(10):7188-7207.
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LPA Induces Metabolic Reprogramming in Ovarian Cancer via a Pseudohypoxic Response. Cancer Res. 2018 04 15; 78(8):1923-1934.
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Adams-Oliver syndrome review of the literature: Refining the diagnostic phenotype. Am J Med Genet A. 2017 Mar; 173(3):790-800.
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Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase. Proc Natl Acad Sci U S A. 2012 Jan 10; 109(2):E59-67.
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Vav and Rac activation in B cell antigen receptor endocytosis involves Vav recruitment to the adapter protein LAB. J Biol Chem. 2009 Dec 25; 284(52):36202-36212.
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Depleting Rac1 in mouse rod photoreceptors protects them from photo-oxidative stress without affecting their structure or function. Proc Natl Acad Sci U S A. 2009 Jun 09; 106(23):9397-402.
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Adaptor protein SLAT modulates Fcgamma receptor-mediated phagocytosis in murine macrophages. J Biol Chem. 2009 May 01; 284(18):11882-91.
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Two domains of cytotoxic necrotizing factor type 1 bind the cellular receptor, laminin receptor precursor protein. Infect Immun. 2007 Nov; 75(11):5095-104.