Electron Transport Complex I
"Electron Transport Complex I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A flavoprotein and iron sulfur-containing oxidoreductase complex that catalyzes the conversion of UBIQUINONE to ubiquinol. In MITOCHONDRIA the complex also couples its reaction to the transport of PROTONS across the internal mitochondrial membrane. The NADH DEHYDROGENASE component of the complex can be isolated and is listed as EC 1.6.99.3.
| Descriptor ID |
D042967
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| MeSH Number(s) |
D05.500.562.249 D08.811.600.250.500.500 D08.811.682.608.504 D12.776.157.427.374.375.863 D12.776.157.530.450.250.875.300 D12.776.331.199.500 D12.776.543.277.500.500 D12.776.543.585.450.250.875.437 D12.776.556.579.374.375.140
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| Concept/Terms |
NADH Dehydrogenase (Ubiquinone)- NADH Dehydrogenase (Ubiquinone)
- NADH Dehydrogenase Complex 1
- NADH Dehydrogenase I
- NADH DH I
- Ubiquinone Reductase
- NADH-Coenzyme Q Reductase
- NADH Coenzyme Q Reductase
- NADH-CoQ Reductase
- NADH CoQ Reductase
- NADH-Ubiquinone Oxidoreductase
- NADH Ubiquinone Oxidoreductase
- Oxidoreductase, NADH-Ubiquinone
- NADH-Ubiquinone Reductase
- NADH Ubiquinone Reductase
- Reductase, NADH-Ubiquinone
- Rotenone-Sensitive Mitochondrial NADH-Ubiquinone Oxidoreductase
- Rotenone Sensitive Mitochondrial NADH Ubiquinone Oxidoreductase
- Complex I Dehydrogenase
- Dehydrogenase, Complex I
- NADH Q1 Oxidoreductase
- Oxidoreductase, NADH Q1
|
Below are MeSH descriptors whose meaning is more general than "Electron Transport Complex I".
Below are MeSH descriptors whose meaning is more specific than "Electron Transport Complex I".
This graph shows the total number of publications written about "Electron Transport Complex I" by people in this website by year, and whether "Electron Transport Complex I" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2016 | 2 | 0 | 2 |
| 2019 | 2 | 0 | 2 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Electron Transport Complex I" by people in Profiles.
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Skeletal muscle mitochondrial interactome remodeling is linked to functional decline in aged female mice. Nat Aging. 2023 Mar; 3(3):313-326.
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Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments. Cell Rep. 2019 09 10; 28(11):2824-2836.e8.
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Microplate Assays for Spectrophotometric Measurement of Mitochondrial Enzyme Activity. Methods Mol Biol. 2019; 1978:355-368.
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AG311, a small molecule inhibitor of complex I and hypoxia-induced HIF-1a stabilization. Cancer Lett. 2017 03 01; 388:149-157.
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Loss of Pink1 modulates synaptic mitochondrial bioenergetics in the rat striatum prior to motor symptoms: concomitant complex I respiratory defects and increased complex II-mediated respiration. Proteomics Clin Appl. 2016 12; 10(12):1205-1217.
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Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry. J Rheumatol. 2013 Jun; 40(6):842-9.
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Reduced mitochondrial ROS, enhanced antioxidant defense, and distinct age-related changes in oxidative damage in muscles of long-lived Peromyscus leucopus. Am J Physiol Regul Integr Comp Physiol. 2013 Mar 01; 304(5):R343-55.
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Chronic caloric restriction preserves mitochondrial function in senescence without increasing mitochondrial biogenesis. Cell Metab. 2012 Dec 05; 16(6):777-88.
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Spatially resolved fluorescence lifetime mapping of enzyme kinetics in living cells. J Microsc. 2008 Jun; 230(Pt 3):329-38.
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Downregulation of ATP synthase subunit-6, cytochrome c oxidase-III, and NADH dehydrogenase-3 by bright cyclic light in the rat retina. Invest Ophthalmol Vis Sci. 2004 Aug; 45(8):2489-96.