MAP Kinase Kinase Kinase 1
"MAP Kinase Kinase Kinase 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 195-kDa zinc finger motif-containing MAP kinase kinase kinase with broad specificity for MAP KINASE KINASES. It localizes to the CYTOSKELETON and can activate a variety of MAP kinase-dependent pathways.
| Descriptor ID |
D048728
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.559.100 D12.644.360.400.100 D12.776.476.400.100
|
| Concept/Terms |
MAP Kinase Kinase Kinase 1- MAP Kinase Kinase Kinase 1
- MEKK1 Protein
- Mitogen-Activated Protein Kinase Kinase Kinase 1
- Mitogen Activated Protein Kinase Kinase Kinase 1
- MEKK-1 Protein Kinase
- MEKK 1 Protein Kinase
- Protein Kinase, MEKK-1
- MEK Kinase 1
- MEKK1 Protein Kinase
- MAP3K1 Protein
- MAP ERK Kinase Kinase 1
|
Below are MeSH descriptors whose meaning is more general than "MAP Kinase Kinase Kinase 1".
Below are MeSH descriptors whose meaning is more specific than "MAP Kinase Kinase Kinase 1".
This graph shows the total number of publications written about "MAP Kinase Kinase Kinase 1" by people in this website by year, and whether "MAP Kinase Kinase Kinase 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
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Below are the most recent publications written about "MAP Kinase Kinase Kinase 1" by people in Profiles.
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Inhibition of nuclear factor-kappaB augments antitumor activity of adenovirus-mediated melanoma differentiation-associated gene-7 against lung cancer cells via mitogen-activated protein kinase kinase kinase 1 activation. Mol Cancer Ther. 2007 Apr; 6(4):1440-9.
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Convergence of signaling pathways on the activation of ERK in B cells. J Biol Chem. 2002 Jun 28; 277(26):23420-6.
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Phorbol ester-induced expression of airway squamous cell differentiation marker, SPRR1B, is regulated by protein kinase Cdelta /Ras/MEKK1/MKK1-dependent/AP-1 signal transduction pathway. J Biol Chem. 2000 Oct 13; 275(41):32250-9.
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Signaling through CD5 involves acidic sphingomyelinase, protein kinase C-zeta, mitogen-activated protein kinase kinase, and c-Jun NH2-terminal kinase. J Immunol. 1999 May 01; 162(9):5149-55.
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p38-2, a novel mitogen-activated protein kinase with distinct properties. J Biol Chem. 1997 Aug 01; 272(31):19509-17.