"Enediynes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds with triple bonds to each side of a double bond. Many of these are CYTOTOXINS and are researched for use as CYTOTOXIC ANTIBIOTICS.
| Descriptor ID |
D053281
|
| MeSH Number(s) |
D02.455.326.271.244 D02.455.326.397.662.500.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Enediynes".
Below are MeSH descriptors whose meaning is more specific than "Enediynes".
This graph shows the total number of publications written about "Enediynes" by people in this website by year, and whether "Enediynes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Enediynes" by people in Profiles.
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Structure-guided functional characterization of enediyne self-sacrifice resistance proteins, CalU16 and CalU19. ACS Chem Biol. 2014 Oct 17; 9(10):2347-58.
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Structural and functional characterization of CalS11, a TDP-rhamnose 3'-O-methyltransferase involved in calicheamicin biosynthesis. ACS Chem Biol. 2013 Jul 19; 8(7):1632-9.
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Glycosyloxyamine neoglycosylation: a model study using calicheamicin. ChemMedChem. 2011 May 02; 6(5):774-6.
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Structural insight into the self-sacrifice mechanism of enediyne resistance. ACS Chem Biol. 2006 Aug 22; 1(7):451-60.
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Differential responses of Chinese hamster mutagen sensitive cell lines to low and high concentrations of calicheamicin and neocarzinostatin. Mutat Res. 2000 Nov 20; 471(1-2):95-105.