"Histidine Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the transferase superfamily of proteins. In the activated state, protein-histidine kinase autophosphorylates at a histidine residue, subsequently transferring high-energy phosphoryl groups to an aspartate residue of the response-regulator domain, which results in a conformational shift in the effector domain. Histidine kinases mediate signal transduction in a wide range of processes involving cellular adaptation to environmental stress.
Descriptor ID |
D000071677
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MeSH Number(s) |
D08.811.913.696.620.682.675
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Concept/Terms |
Histidine Kinase- Histidine Kinase
- Kinase, Histidine
- Histidine Protein Kinase
- Kinase, Histidine Protein
- Protein Kinase, Histidine
- Protein-Histidine Kinase
- Kinase, Protein-Histidine
- Protein Histidine Kinase
Protein Histidine Pros-Kinase- Protein Histidine Pros-Kinase
- Histidine Pros-Kinase, Protein
- Pros-Kinase, Protein Histidine
- Protein Histidine Pros Kinase
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Below are MeSH descriptors whose meaning is more general than "Histidine Kinase".
Below are MeSH descriptors whose meaning is more specific than "Histidine Kinase".
This graph shows the total number of publications written about "Histidine Kinase" by people in this website by year, and whether "Histidine Kinase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 1 | 1 |
2003 | 0 | 1 | 1 |
2004 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
2021 | 0 | 2 | 2 |
2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Histidine Kinase" by people in Profiles.
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Analysis of CheW-like domains provides insights into organization of prokaryotic chemotaxis systems. Proteins. 2023 03; 91(3):315-329.
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Generalizable strategy to analyze domains in the context of parent protein architecture: A CheW case study. Proteins. 2022 11; 90(11):1973-1986.
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Predicted Functional and Structural Diversity of Receiver Domains in Fungal Two-Component Regulatory Systems. mSphere. 2021 10 27; 6(5):e0072221.
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A Radical Reimagining of Fungal Two-Component Regulatory Systems. Trends Microbiol. 2021 10; 29(10):883-893.
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Novel genomic rearrangements mediated by multiple genetic elements in Streptococcus pyogenes M23ND confer potential for evolutionary persistence. Microbiology (Reading). 2016 08; 162(8):1346-1359.
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Two-component phosphorelays in fungal mitochondria and beyond. Mitochondrion. 2015 May; 22:60-5.
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The hybrid histidine kinase Hk1 is part of a two-component system that is essential for survival of Borrelia burgdorferi in feeding Ixodes scapularis ticks. Infect Immun. 2011 Aug; 79(8):3117-30.
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Studies on the regulation of the two-component histidine kinase gene CHK1 in Candida albicans using the heterologous lacZ reporter gene. Microbiology (Reading). 2004 Oct; 150(Pt 10):3305-13.
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MASE1 and MASE2: two novel integral membrane sensory domains. J Mol Microbiol Biotechnol. 2003; 5(1):11-6.
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Histidine kinases and response regulator proteins in two-component signaling systems. Trends Biochem Sci. 2001 Jun; 26(6):369-76.