"Phospholipase C gamma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phosphoinositide phospholipase C subtype that is primarily regulated by PROTEIN-TYROSINE KINASES. It is structurally related to PHOSPHOLIPASE C DELTA with the addition of SRC HOMOLOGY DOMAINS and pleckstrin homology domains located between two halves of the CATALYTIC DOMAIN.
| Descriptor ID |
D051966
|
| MeSH Number(s) |
D08.811.277.352.640.700.700.562.750 D12.644.360.571.750 D12.776.476.556.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Phospholipase C gamma".
Below are MeSH descriptors whose meaning is more specific than "Phospholipase C gamma".
This graph shows the total number of publications written about "Phospholipase C gamma" by people in this website by year, and whether "Phospholipase C gamma" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 3 | 3 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 1 | 2 |
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Below are the most recent publications written about "Phospholipase C gamma" by people in Profiles.
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Immunohistochemical analysis of the natural killer cell cytotoxicity pathway in human abdominal aortic aneurysms. Int J Mol Sci. 2015 May 18; 16(5):11196-212.
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Phospholipase C-gamma2 is essential for NK cell cytotoxicity and innate immunity to malignant and virally infected cells. Blood. 2006 Feb 01; 107(3):994-1002.
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PKD2 functions as an epidermal growth factor-activated plasma membrane channel. Mol Cell Biol. 2005 Sep; 25(18):8285-98.
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PLCgamma2 regulates Bcl-2 levels and is required for survival rather than differentiation of marginal zone and follicular B cells. Eur J Immunol. 2004 Aug; 34(8):2237-47.
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A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation. J Exp Med. 2002 Sep 16; 196(6):753-63.
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Convergence of signaling pathways on the activation of ERK in B cells. J Biol Chem. 2002 Jun 28; 277(26):23420-6.
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C-reactive protein induces signaling through Fc gamma RIIa on HL-60 granulocytes. J Immunol. 2002 Feb 01; 168(3):1413-8.
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The adapter protein LAT enhances fcgamma receptor-mediated signal transduction in myeloid cells. J Biol Chem. 2000 Jul 07; 275(27):20480-7.
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Analysis of tyrosine phosphorylation-dependent interactions between stimulatory effector proteins and the B cell co-receptor CD22. J Biol Chem. 1999 Jun 25; 274(26):18769-76.
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Phospholipase Cgamma1 in bovine rod outer segments: immunolocalization and light-dependent binding to membranes. J Neurochem. 1998 Jan; 70(1):171-8.