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Expression of common chromosomal fragile site genes, WWOX/FRA16D and FHIT/FRA3B is downregulated by exposure to environmental carcinogens, UV, and BPDE but not by IR.
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Expression of common chromosomal fragile site genes, WWOX/FRA16D and FHIT/FRA3B is downregulated by exposure to environmental carcinogens, UV, and BPDE but not by IR.
Expression of common chromosomal fragile site genes, WWOX/FRA16D and FHIT/FRA3B is downregulated by exposure to environmental carcinogens, UV, and BPDE but not by IR. Mol Carcinog. 2005 Nov; 44(3):174-82.
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7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
Acid Anhydride Hydrolases
Acid Anhydride Hydrolases
Carcinogens, Environmental
Carcinogens, Environmental
Cell Line, Tumor
Cell Line, Tumor
Chromosome Fragile Sites
Chromosome Fragile Sites
Down-Regulation
Down-Regulation
Gene Expression Regulation, Neoplastic
Gene Expression Regulation, Neoplastic
Humans
Humans
Neoplasm Proteins
Neoplasm Proteins
Oxidoreductases
Oxidoreductases
Radiation, Ionizing
Radiation, Ionizing
Tumor Suppressor Protein p53
Tumor Suppressor Protein p53
Tumor Suppressor Proteins
Tumor Suppressor Proteins
Ultraviolet Rays
Ultraviolet Rays
WW Domain-Containing Oxidoreductase
WW Domain-Containing Oxidoreductase