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Forward genetic screening identifies a small molecule that blocks Toxoplasma gondii growth by inhibiting both host- and parasite-encoded kinases.
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Forward genetic screening identifies a small molecule that blocks Toxoplasma gondii growth by inhibiting both host- and parasite-encoded kinases.
Forward genetic screening identifies a small molecule that blocks Toxoplasma gondii growth by inhibiting both host- and parasite-encoded kinases. PLoS Pathog. 2014 Jun; 10(6):e1004180.
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PubMed
subject areas
Activin Receptors, Type I
Activin Receptors, Type I
Animals
Animals
Base Sequence
Base Sequence
Benzodioxoles
Benzodioxoles
Catalytic Domain
Catalytic Domain
DNA, Protozoan
DNA, Protozoan
Drug Resistance
Drug Resistance
Genome, Protozoan
Genome, Protozoan
Host-Parasite Interactions
Host-Parasite Interactions
Hypoxia-Inducible Factor 1
Hypoxia-Inducible Factor 1
Imidazoles
Imidazoles
Mice
Mice
Mice, Inbred C57BL
Mice, Inbred C57BL
Mitogen-Activated Protein Kinase 1
Mitogen-Activated Protein Kinase 1
Protozoan Proteins
Protozoan Proteins
Pyridines
Pyridines
Sequence Analysis, DNA
Sequence Analysis, DNA
Signal Transduction
Signal Transduction
Toxoplasma
Toxoplasma
authors with profiles
Patrick Gaffney
Kevin Michael Brown