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Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation.
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Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation.
Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation. Cell Rep. 2015 Jun 09; 11(9):1458-73.
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PubMed
subject areas
Animals
Animals
Cell Line, Tumor
Cell Line, Tumor
Chromatography, Liquid
Chromatography, Liquid
Down-Regulation
Down-Regulation
Drug Resistance, Neoplasm
Drug Resistance, Neoplasm
Enzyme Inhibitors
Enzyme Inhibitors
Female
Female
Heterografts
Heterografts
Humans
Humans
Immunoblotting
Immunoblotting
Immunohistochemistry
Immunohistochemistry
Immunoprecipitation
Immunoprecipitation
Janus Kinase 1
Janus Kinase 1
Mass Spectrometry
Mass Spectrometry
Melanoma
Melanoma
Mice
Mice
Mice, Nude
Mice, Nude
Proto-Oncogene Proteins B-raf
Proto-Oncogene Proteins B-raf
RNA, Small Interfering
RNA, Small Interfering
Transfection
Transfection
Ubiquitin-Protein Ligases
Ubiquitin-Protein Ligases
authors with profiles
Kevin Michael Brown