"Fucosyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes catalyzing the transfer of fucose from a nucleoside diphosphate fucose to an acceptor molecule which is frequently another carbohydrate, a glycoprotein, or a glycolipid molecule. Elevated activity of some fucosyltransferases in human serum may serve as an indicator of malignancy. The class includes EC 2.4.1.65; EC 2.4.1.68; EC 2.4.1.69; EC 2.4.1.89.
| Descriptor ID |
D005647
|
| MeSH Number(s) |
D08.811.913.400.450.300
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Fucosyltransferases".
Below are MeSH descriptors whose meaning is more specific than "Fucosyltransferases".
This graph shows the total number of publications written about "Fucosyltransferases" by people in this website by year, and whether "Fucosyltransferases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Fucosyltransferases" by people in Profiles.
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Partners in crime: The Lewis Y antigen and fucosyltransferase IV in Helicobacter pylori-induced gastric cancer. Pharmacol Ther. 2022 04; 232:107994.
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FUT2 genotype influences lung function, exacerbation frequency and airway microbiota in non-CF bronchiectasis. Thorax. 2017 Apr; 72(4):304-310.
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Surface fucosylation of human cord blood cells augments binding to P-selectin and E-selectin and enhances engraftment in bone marrow. Blood. 2004 Nov 15; 104(10):3091-6.
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N-terminal residues in murine P-selectin glycoprotein ligand-1 required for binding to murine P-selectin. Blood. 2003 Jan 15; 101(2):552-9.
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Post-translational modifications of recombinant P-selectin glycoprotein ligand-1 required for binding to P- and E-selectin. J Biol Chem. 1996 Feb 09; 271(6):3255-64.