"Galactosylceramides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cerebrosides which contain as their polar head group a galactose moiety bound in glycosidic linkage to the hydroxyl group of ceramide. Their accumulation in tissue, due to a defect in beta-galactosidase, is the cause of galactosylceramide lipidosis or globoid cell leukodystrophy.
| Descriptor ID |
D005699
|
| MeSH Number(s) |
D02.065.313.250.450 D09.400.410.420.525.200.250.450 D10.390.470.675.200.250.450 D10.570.877.360.612.200.250.450
|
| Concept/Terms |
Galactosylceramides- Galactosylceramides
- Galactosyl Ceramides
- Ceramides, Galactosyl
- Galactocerebrosides
|
Below are MeSH descriptors whose meaning is more general than "Galactosylceramides".
Below are MeSH descriptors whose meaning is more specific than "Galactosylceramides".
This graph shows the total number of publications written about "Galactosylceramides" by people in this website by year, and whether "Galactosylceramides" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Galactosylceramides" by people in Profiles.
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a-Galactosylceramide-Reactive NKT Cells Increase IgG1 Class Switch against a Clostridioides difficile Polysaccharide Antigen and Enhance Immunity against a Live Pathogen Challenge. Infect Immun. 2021 10 15; 89(11):e0043821.
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Immunization-Expanded NKT Follicular Helper Cells Drive IgG1 Isotype Switch against an Exogenous T-Independent Polysaccharide but Do Not Promote Recall Responses. Immunohorizons. 2019 03; 3(3):88-93.
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Coordination between T helper cells, iNKT cells, and their follicular helper subsets in the humoral immune response against Clostridium difficile toxin B. J Leukoc Biol. 2017 02; 101(2):567-576.
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CD1d-dependent expansion of NKT follicular helper cells in vivo and in vitro is a product of cellular proliferation and differentiation. Int Immunol. 2015 May; 27(5):253-63.
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BAFF- and APRIL-dependent maintenance of antibody titers after immunization with T-dependent antigen and CD1d-binding ligand. J Immunol. 2013 Aug 01; 191(3):1154-63.
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Natural IgM anti-leukocyte autoantibodies attenuate excess inflammation mediated by innate and adaptive immune mechanisms involving Th-17. J Immunol. 2012 Feb 15; 188(4):1675-85.
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Reduction of CD1d expression in vivo minimally affects NKT-enhanced antibody production but boosts B-cell memory. Int Immunol. 2011 Apr; 23(4):251-60.
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CD1d-dependent B-cell help by NK-like T cells leads to enhanced and sustained production of Bacillus anthracis lethal toxin-neutralizing antibodies. Infect Immun. 2010 Apr; 78(4):1610-7.
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Bacillus anthracis lethal toxin disrupts TCR signaling in CD1d-restricted NKT cells leading to functional anergy. PLoS Pathog. 2009 Sep; 5(9):e1000588.
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Requirement for CD1d expression by B cells to stimulate NKT cell-enhanced antibody production. Blood. 2008 Feb 15; 111(4):2158-62.