"Transaminases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of enzymes of the transferase class that catalyze the transfer of an amino group from a donor (generally an amino acid) to an acceptor (generally a 2-keto acid). Most of these enzymes are pyridoxyl phosphate proteins. (Dorland, 28th ed) EC 2.6.1.
| Descriptor ID |
D000637
|
| MeSH Number(s) |
D08.811.913.477.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Transaminases".
Below are MeSH descriptors whose meaning is more specific than "Transaminases".
This graph shows the total number of publications written about "Transaminases" by people in this website by year, and whether "Transaminases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 2 | 0 | 2 |
| 2002 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2015 | 1 | 1 | 2 |
| 2018 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transaminases" by people in Profiles.
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Gut-restricted apical sodium-dependent bile acid transporter inhibitor attenuates alcohol-induced liver steatosis and injury in mice. Alcohol Clin Exp Res. 2021 06; 45(6):1188-1199.
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Ranitidine-Associated Autoimmune Hepatitis. Am J Ther. 2018 Nov/Dec; 25(6):e758-e760.
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Nonalcoholic fatty liver disease: a potential consequence of tumor necrosis factor-inhibitor therapy. Eur J Gastroenterol Hepatol. 2015 Oct; 27(10):1154-60.
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Structural Basis for the Stereochemical Control of Amine Installation in Nucleotide Sugar Aminotransferases. ACS Chem Biol. 2015 Sep 18; 10(9):2048-56.
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Crystalline retinopathy in primary hyperoxaluria. J AAPOS. 2011 Apr; 15(2):214-6.
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Chronic alcohol-induced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice. Free Radic Biol Med. 2010 Nov 15; 49(9):1406-16.
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Detection of a gem-diamine and a stable quinonoid intermediate in the reaction catalyzed by serine-glyoxylate aminotransferase from Hyphomicrobium methylovorum. Biochim Biophys Acta. 2009 Jun; 1790(6):575-80.
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Metabolism of cisplatin to a nephrotoxin. Toxicology. 2009 Mar 29; 257(3):174-5; author reply 176-7.
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Reaction of serine-glyoxylate aminotransferase with the alternative substrate ketomalonate indicates rate-limiting protonation of a quinonoid intermediate. Biochemistry. 2005 Dec 06; 44(48):15930-6.
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Role of cysteine S-conjugate beta-lyase in the metabolism of cisplatin. J Pharmacol Exp Ther. 2003 Sep; 306(3):988-94.