"Hyaluronan Synthases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane-associated glucuronosyltransferases that catalyze the reaction of UDP-N-acetyl-D-glucosamine and UDP-D-glucuronate to produce HYALURONAN. HYALURONAN SYNTHASE 2 (HAS2) is essential for embryogenesis and its expression by tumor cells is associated with metastasis.
| Descriptor ID |
D000076002
|
| MeSH Number(s) |
D08.811.913.400.450.480.500
|
| Concept/Terms |
Hyaluronan Synthases- Hyaluronan Synthases
- Synthases, Hyaluronan
- Hyaluronan Synthase
- Synthase, Hyaluronan
- Hyaluronic Acid Synthetase
- Synthetase, Hyaluronic Acid
- Hyaluronate Synthetase
- Synthetase, Hyaluronate
- Hyaluronan Synthetase
- Synthetase, Hyaluronan
- Hyaluronate Synthase
- Synthase, Hyaluronate
Hyaluronan Synthase 3- Hyaluronan Synthase 3
- 3, Hyaluronan Synthase
- Synthase 3, Hyaluronan
- HAS3 Protein
- Protein, HAS3
|
Below are MeSH descriptors whose meaning is more general than "Hyaluronan Synthases".
Below are MeSH descriptors whose meaning is more specific than "Hyaluronan Synthases".
This graph shows the total number of publications written about "Hyaluronan Synthases" by people in this website by year, and whether "Hyaluronan Synthases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hyaluronan Synthases" by people in Profiles.
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CPAP-induced airway hyper-reactivity in mice is modulated by hyaluronan synthase-3. Pediatr Res. 2022 09; 92(3):685-693.
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Hyaluronan synthase assembles hyaluronan on a [GlcNAc(ß1,4)]n-GlcNAc(a1?)UDP primer and hyaluronan retains this residual chitin oligomer as a cap at the nonreducing end. Glycobiology. 2017 06 01; 27(6):536-554.
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Hyaluronan synthase control of synthesis rate and hyaluronan product size are independent functions differentially affected by mutations in a conserved tandem B-X7-B motif. Glycobiology. 2017 01; 27(2):154-164.
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Hyaluronan synthase assembles chitin oligomers with -GlcNAc(a1?)UDP at the reducing end. Glycobiology. 2015 Jun; 25(6):632-43.
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Hyaluronan in cytosol--microinjection-based probing of its existence and suggested functions. Glycobiology. 2013 Feb; 23(2):222-31.
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Hyaluronan synthase mediates dye translocation across liposomal membranes. BMC Biochem. 2012 Jan 25; 13:2.
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Monodisperse hyaluronan polymers: synthesis and potential applications. Curr Pharm Biotechnol. 2008 Aug; 9(4):246-8.
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Hyaluronan synthases: a decade-plus of novel glycosyltransferases. J Biol Chem. 2007 Dec 21; 282(51):36777-81.
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Acceptor specificity of the Pasteurella hyaluronan and chondroitin synthases and production of chimeric glycosaminoglycans. J Biol Chem. 2007 Jan 05; 282(1):337-44.
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The functional molecular mass of the Pasteurella hyaluronan synthase is a monomer. Biochim Biophys Acta. 2007 Feb; 1770(2):286-90.