"Bile Acids and Salts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Steroid acids and salts. The primary bile acids are derived from cholesterol in the liver and usually conjugated with glycine or taurine. The secondary bile acids are further modified by bacteria in the intestine. They play an important role in the digestion and absorption of fat. They have also been used pharmacologically, especially in the treatment of gallstones.
| Descriptor ID |
D001647
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| MeSH Number(s) |
D04.210.500.105
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Bile Acids and Salts".
Below are MeSH descriptors whose meaning is more specific than "Bile Acids and Salts".
This graph shows the total number of publications written about "Bile Acids and Salts" by people in this website by year, and whether "Bile Acids and Salts" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 0 | 3 | 3 |
| 2019 | 0 | 1 | 1 |
| 2021 | 0 | 3 | 3 |
| 2023 | 1 | 1 | 2 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Bile Acids and Salts" by people in Profiles.
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Deletion of hepatocyte cysteine dioxygenase type 1, a bile acid repressed gene, enhances glutathione synthesis and ameliorates acetaminophen hepatotoxicity. Biochem Pharmacol. 2024 Apr; 222:116103.
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Glycine-?-Muricholic Acid Improves Liver Fibrosis and Gut Barrier Function by Reducing Bile Acid Pool Size and Hydrophobicity in Male Cyp2c70 Knockout Mice. Cells. 2023 05 12; 12(10).
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Combining ASBT inhibitor and FGF15 treatments enhances therapeutic efficacy against cholangiopathy in female but not male Cyp2c70 KO mice. J Lipid Res. 2023 03; 64(3):100340.
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Cholbam® and Zellweger spectrum disorders: treatment implementation and management. Orphanet J Rare Dis. 2021 09 14; 16(1):388.
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Gut-restricted apical sodium-dependent bile acid transporter inhibitor attenuates alcohol-induced liver steatosis and injury in mice. Alcohol Clin Exp Res. 2021 06; 45(6):1188-1199.
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Combined ASBT Inhibitor and FGF15 Treatment Improves Therapeutic Efficacy in Experimental Nonalcoholic Steatohepatitis. Cell Mol Gastroenterol Hepatol. 2021; 12(3):1001-1019.
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An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis. Nat Commun. 2020 07 17; 11(1):3612.
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Regular exercise potentiates energetically expensive hepatic de novo lipogenesis during early weight regain. Am J Physiol Regul Integr Comp Physiol. 2019 11 01; 317(5):R684-R695.
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The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD. Nat Commun. 2018 10 26; 9(1):4462.
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HNF4a Regulates CSAD to Couple Hepatic Taurine Production to Bile Acid Synthesis in Mice. Gene Expr. 2018 08 22; 18(3):187-196.