Osteopontin contributes to virus resistance associated with type I IFN expression, activation of downstream ifn-inducible effector genes, and CCR2+CD115+CD206+ macrophage infiltration following ocular HSV-1 infection of mice.

Osteopontin contributes to virus resistance associated with type I IFN expression, activation of downstream ifn-inducible effector genes, and CCR2+CD115+CD206+ macrophage infiltration following ocular HSV-1 infection of mice. Front Immunol. 2022; 13:1028341.

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subject areas

Animals
CD8-Positive T-Lymphocytes
Herpes Simplex
Herpesvirus 1, Human
Inflammation
Keratitis, Herpetic
Macrophages
Mice
Mice, Inbred C57BL
Osteopontin
Receptors, CCR2
Vascular Endothelial Growth Factor A