Lymphocyte Culture Test, Mixed
"Lymphocyte Culture Test, Mixed" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.
Descriptor ID |
D007959
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MeSH Number(s) |
E01.370.225.812.385.475 E05.200.812.385.475 E05.478.594.385.429
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Concept/Terms |
Lymphocyte Culture Test, Mixed- Lymphocyte Culture Test, Mixed
- Leukocyte Culture Test, Mixed
- Mixed Lymphocyte Reaction
- Lymphocyte Reaction, Mixed
- Lymphocyte Reactions, Mixed
- Mixed Lymphocyte Reactions
- Mixed Leukocyte Reaction
- Leukocyte Reaction, Mixed
- Leukocyte Reactions, Mixed
- Mixed Leukocyte Reactions
- Mixed Leukocyte Culture Test
- Mixed Lymphocyte Culture Test
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Below are MeSH descriptors whose meaning is more general than "Lymphocyte Culture Test, Mixed".
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This graph shows the total number of publications written about "Lymphocyte Culture Test, Mixed" by people in this website by year, and whether "Lymphocyte Culture Test, Mixed" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lymphocyte Culture Test, Mixed" by people in Profiles.
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Nucleotide sequence analysis of HLA-B*1523 and B*8101. Dominant alpha-helical motifs produce complex serologic recognition patterns for the HLA-B"DT" and HLA-B"NM5" antigens. Hum Immunol. 1995 Oct; 44(2):103-10.
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Involvement of the CDw50 molecule in allorecognition. Tissue Antigens. 1990 Nov; 36(5):203-10.