Myosin-Light-Chain Kinase
"Myosin-Light-Chain Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that phosphorylates myosin light chains in the presence of ATP to yield myosin-light chain phosphate and ADP, and requires calcium and CALMODULIN. The 20-kDa light chain is phosphorylated more rapidly than any other acceptor, but light chains from other myosins and myosin itself can act as acceptors. The enzyme plays a central role in the regulation of smooth muscle contraction.
| Descriptor ID |
D009219
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.125.500 D12.644.360.100.500 D12.776.476.100.500
|
| Concept/Terms |
Myosin-Light-Chain Kinase- Myosin-Light-Chain Kinase
- Kinase, Myosin-Light-Chain
- Myosin Light Chain Kinase
- Myosin Regulatory Light-Chain Kinase
- Myosin Regulatory Light Chain Kinase
- Myosin Kinase
- Kinase, Myosin
- Myosin LCK
- LCK, Myosin
|
Below are MeSH descriptors whose meaning is more general than "Myosin-Light-Chain Kinase".
Below are MeSH descriptors whose meaning is more specific than "Myosin-Light-Chain Kinase".
This graph shows the total number of publications written about "Myosin-Light-Chain Kinase" by people in this website by year, and whether "Myosin-Light-Chain Kinase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
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Below are the most recent publications written about "Myosin-Light-Chain Kinase" by people in Profiles.
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Genetic Inactivation of Chlamydia trachomatis Inclusion Membrane Protein CT228 Alters MYPT1 Recruitment, Extrusion Production, and Longevity of Infection. Front Cell Infect Microbiol. 2018; 8:415.
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Preserved expression of GLUT4 prevents enhanced agonist-induced vascular reactivity and MYPT1 phosphorylation in hypertensive mouse aorta. Am J Physiol Heart Circ Physiol. 2007 Jul; 293(1):H402-8.
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Regulation of LPA-promoted myofibroblast contraction: role of Rho, myosin light chain kinase, and myosin light chain phosphatase. Exp Cell Res. 2000 Feb 01; 254(2):210-20.