| Item Type | Name |
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Concept
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Tumor Protein p73
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Concept
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Oncogene Protein pp60(v-src)
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Concept
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Protein Structure, Secondary
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Concept
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Protein Structure, Tertiary
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Concept
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Protein Tyrosine Phosphatases
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Concept
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Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
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Concept
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Mitogen-Activated Protein Kinase 1
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Concept
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Protein Isoforms
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Concept
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Protein Binding
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Concept
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Protein Conformation
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Concept
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Protein Kinases
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Concept
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Protein Processing, Post-Translational
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Concept
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Protein-Tyrosine Kinases
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Concept
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HMGA1a Protein
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Concept
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bcl-2 Homologous Antagonist-Killer Protein
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Concept
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bcl-2-Associated X Protein
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Concept
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Protein Kinase Inhibitors
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Concept
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p38 Mitogen-Activated Protein Kinases
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Concept
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Mitogen-Activated Protein Kinase 3
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Concept
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Receptor-Interacting Protein Serine-Threonine Kinases
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Concept
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Protein Tyrosine Phosphatase, Non-Receptor Type 6
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Concept
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Proto-Oncogene Protein c-ets-1
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Concept
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Mitogen-Activated Protein Kinases
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Concept
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Protein Transport
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Concept
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Protein Tyrosine Phosphatases, Non-Receptor
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Concept
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Protein Tyrosine Phosphatase, Non-Receptor Type 1
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Concept
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Protein Tyrosine Phosphatase, Non-Receptor Type 11
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Concept
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SH2 Domain-Containing Protein Tyrosine Phosphatases
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Concept
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Protein Tyrosine Phosphatase, Non-Receptor Type 22
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Concept
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Protein Phosphatase 1
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Concept
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Immunoglobulin J Recombination Signal Sequence-Binding Protein
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Concept
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Smad3 Protein
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Academic Article
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Substrate specificity of protein tyrosine phosphatase: differential behavior of SHP-1 and SHP-2 towards signal regulation protein SIRPalpha1.
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Academic Article
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MAPK-activated protein kinase-2 (MK2)-mediated formation and phosphorylation-regulated dissociation of the signal complex consisting of p38, MK2, Akt, and Hsp27.
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Academic Article
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Cell density-dependent regulation of p73 in breast cancer cells.
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Academic Article
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Identification of a variant form of tyrosine phosphatase LYP.
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Academic Article
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Crystal structure of human protein tyrosine phosphatase SHP-1 in the open conformation.
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Academic Article
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The small molecule inhibitor G6 significantly reduces bone marrow fibrosis and the mutant burden in a mouse model of Jak2-mediated myelofibrosis.
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Academic Article
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Generation and characterization of a highly effective protein substrate for analysis of FLT3 activity.
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Academic Article
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SU11652 Inhibits tyrosine kinase activity of FLT3 and growth of MV-4-11 cells.
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Academic Article
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Elevated levels of mast cells are involved in pruritus associated with polycythemia vera in JAK2V617F transgenic mice.
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Academic Article
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Specific dephosphorylation of Janus Kinase 2 by protein tyrosine phosphatases.
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Academic Article
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The Protein Tyrosine Phosphatase MEG2 Regulates the Transport and Signal Transduction of Tropomyosin Receptor Kinase A.
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Academic Article
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CRISPR/Cas9 Knockout of Bak Mediates Bax Translocation to Mitochondria in response to TNFa/CHX-induced Apoptosis.
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Academic Article
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Loss of tyrosine phosphatase SHP2 activity promotes growth of colorectal carcinoma HCT-116 cells.
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Academic Article
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SPAP2, an Ig family receptor containing both ITIMs and ITAMs.
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Academic Article
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Specific interaction of protein tyrosine phosphatase-MEG2 with phosphatidylserine.
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Academic Article
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Tyrosine phosphorylation of phospholipase D1 by v-Src does not per se result in activation.
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Academic Article
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Role of tyrosine kinases and phosphatases in polycythemia vera.
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Academic Article
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Erlotinib effectively inhibits JAK2V617F activity and polycythemia vera cell growth.
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Academic Article
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Characterization of a highly effective protein substrate for analysis of JAK2(V617F) Activity.
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Academic Article
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Characterization and functional studies of a FYVE domain-containing phosphatase in C. elegans.
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Academic Article
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Protein tyrosine phosphatase Meg2 dephosphorylates signal transducer and activator of transcription 3 and suppresses tumor growth in breast cancer.
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Academic Article
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RBPJ mutations identified in two families affected by Adams-Oliver syndrome.
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Academic Article
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Generation and characterization of a JAK2V617F-containing erythroleukemia cell line.
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Academic Article
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Molecular cloning and characterization of a tyrosine phosphatase from Monosiga brevicollis.
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Academic Article
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Proapoptotic Mitochondrial Carrier Homolog Protein PSAP Mediates Death Receptor 6 Induced Apoptosis.
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Academic Article
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Blocking the function of tyrosine phosphatase SHP-2 by targeting its Src homology 2 domains.
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Academic Article
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PTP-MEG2 is activated in polycythemia vera erythroid progenitor cells and is required for growth and expansion of erythroid cells.
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Academic Article
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PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells.
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Academic Article
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Identification of an acquired JAK2 mutation in polycythemia vera.
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Academic Article
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Tyrosine phosphatase MEG2 modulates murine development and platelet and lymphocyte activation through secretory vesicle function.
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Academic Article
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Antagonism or synergism. Role of tyrosine phosphatases SHP-1 and SHP-2 in growth factor signaling.
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Academic Article
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The Jak2 inhibitor, G6, alleviates Jak2-V617F-mediated myeloproliferative neoplasia by providing significant therapeutic efficacy to the bone marrow.
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Academic Article
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Caenorhabditis elegans eyes absent ortholog EYA-1 is required for stress resistance.
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Academic Article
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Tyrosine phosphatases SHP-1 and SHP-2 are associated with distinct tyrosine-phosphorylated proteins.
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Academic Article
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Crystal structure of human protein-tyrosine phosphatase SHP-1.
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Academic Article
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Tea contains potent inhibitors of tyrosine phosphatase PTP1B.
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Academic Article
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Myotubularin family phosphatase ceMTM3 is required for muscle maintenance by preventing excessive autophagy in Caenorhabditis elegans.
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Academic Article
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Transposon mutagenesis reveals cooperation of ETS family transcription factors with signaling pathways in erythro-megakaryocytic leukemia.
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Academic Article
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Efficacy of ALK5 inhibition in myelofibrosis.
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Academic Article
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miR-543 regulates the epigenetic landscape of myelofibrosis by targeting TET1 and TET2.
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Grant
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PROTEIN TYROSINE PHOSPHATASES IN POLYCYTHEMIA VERA
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Grant
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TYROSINE PHOSPHATASES IN SIGNAL TRANSDUCTION
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Grant
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Tyrosine Phosphatase in Signal Transduction
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Grant
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Tyrosine Phosphatase PTP-MEG2 and Hematopoiesis
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Academic Article
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Association of PTPN22-C1858T Polymorphism With Susceptibility to Mycobacterium tuberculosis and Mycobacterium leprae Infection: A Meta-Analysis.
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Academic Article
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HMGA1 chromatin regulators induce transcriptional networks involved in GATA2 and proliferation during MPN progression.
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Academic Article
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Efficacy of SCF drug conjugate targeting c-KIT in gastrointestinal stromal tumor.
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Academic Article
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SHP-1 dephosphorylates 3BP2 and potentially downregulates 3BP2-mediated T cell antigen receptor signaling.
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Academic Article
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Protein-tyrosine phosphatase PTPN9 negatively regulates ErbB2 and epidermal growth factor receptor signaling in breast cancer cells.
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Academic Article
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Enhanced RIPK3 kinase activity-dependent lytic cell death in M1 but not M2 macrophages.
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