| Item Type | Name |
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Concept
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Mice, Inbred BALB C
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Concept
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Mice, Inbred C57BL
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Concept
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Mice, Inbred DBA
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Concept
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Mice, Inbred ICR
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Concept
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Mice, Mutant Strains
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Concept
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Mice, Transgenic
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Concept
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Mice, SCID
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Concept
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Mice, Knockout
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Concept
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Mice
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Academic Article
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Differential effect of murine alpha/beta interferon transgenes on antagonization of herpes simplex virus type 1 replication.
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Academic Article
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"Amyloid-beta accumulation cycle" as a prevention and/or therapy target for Alzheimer's disease.
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Academic Article
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Microglia and a functional type I IFN pathway are required to counter HSV-1-driven brain lateral ventricle enlargement and encephalitis.
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Academic Article
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Large-scale generation of plasmids that express type I interferon.
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Academic Article
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Dichotomy between survival and lytic gene expression in RNase L- and PKR-deficient mice transduced with an adenoviral vector expressing murine IFN-beta following ocular HSV-1 infection.
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Academic Article
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Abnormal immune response of CCR5-deficient mice to ocular infection with herpes simplex virus type 1.
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Academic Article
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CXCL10 expressing hematopoietic-derived cells are requisite in defense against HSV-1 infection in the nervous system of CXCL10 deficient mice.
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Academic Article
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Tumor necrosis factor alpha and interleukin-6 facilitate corneal lymphangiogenesis in response to herpes simplex virus 1 infection.
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Academic Article
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Cornea lymphatics drive the CD8+ T-cell response to herpes simplex virus-1.
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Academic Article
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Long-term consequences of topical dexamethasone treatment during acute corneal HSV-1 infection on the immune system.
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Academic Article
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Impact of Type I Interferon on the Safety and Immunogenicity of an Experimental Live-Attenuated Herpes Simplex Virus 1 Vaccine in Mice.
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Academic Article
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Colony Stimulating Factor-1 Receptor Expressing Cells Infiltrating the Cornea Control Corneal Nerve Degeneration in Response to HSV-1 Infection.
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Academic Article
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Vaccine-induced antibodies target sequestered viral antigens to prevent ocular HSV-1 pathogenesis, preserve vision, and preempt productive neuronal infection.
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Academic Article
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Ocular Glands Become Infected Secondarily to Infectious Keratitis and Play a Role in Corneal Resistance to Infection.
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Academic Article
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An opposing time-dependent immune-modulating effect of the sympathetic nervous system conferred by altering the cytokine profile in the local lymph nodes and spleen of mice with type II collagen-induced arthritis.
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Academic Article
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Chemokine receptor deficiency is associated with increased chemokine expression in the peripheral and central nervous systems and increased resistance to herpetic encephalitis.
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Academic Article
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OAS and PKR are not required for the antiviral effect of Ad:IFN-gamma against acute HSV-1 in primary trigeminal ganglia cultures.
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Academic Article
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Herpes simplex virus type 1 induction of chemokine production is unrelated to viral load in the cornea but not in the nervous system.
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Academic Article
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An increase in herpes simplex virus type 1 in the anterior segment of the eye is linked to a deficiency in NK cell infiltration in mice deficient in CXCR3.
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Academic Article
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Insertion of the CXC chemokine ligand 9 (CXCL9) into the mouse hepatitis virus genome results in protection from viral-induced encephalitis and hepatitis.
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Academic Article
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Dysregulation of CXCR3 signaling due to CXCL10 deficiency impairs the antiviral response to herpes simplex virus 1 infection.
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Academic Article
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Delivery of Interferon-gamma by an adenovirus vector blocks herpes simplex virus Type 1 reactivation in vitro and in vivo independent of RNase L and double-stranded RNA-dependent protein kinase pathways.
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Academic Article
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VEGF-A expression by HSV-1-infected cells drives corneal lymphangiogenesis.
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Academic Article
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Loss of the type I interferon pathway increases vulnerability of mice to genital herpes simplex virus 2 infection.
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Academic Article
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The herpes simplex virus-1 transactivator infected cell protein-4 drives VEGF-A dependent neovascularization.
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Academic Article
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CXCL1-deficient mice are highly sensitive to pseudomonas aeruginosa but not herpes simplex virus type 1 corneal infection.
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Academic Article
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Granulocytes in Ocular HSV-1 Infection: Opposing Roles of Mast Cells and Neutrophils.
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Academic Article
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Type I Interferons Induce T Regulatory 1 Responses and Restrict Humoral Immunity during Experimental Malaria.
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Academic Article
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Herpes simplex virus-1 infects the olfactory bulb shortly following ocular infection and exhibits a long-term inflammatory profile in the form of effector and HSV-1-specific T cells.
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Academic Article
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Herpes Simplex Virus 1 (HSV-1) 0?NLS Live-Attenuated Vaccine Protects against Ocular HSV-1 Infection in the Absence of Neutralizing Antibody in HSV-1 gB T Cell Receptor-Specific Transgenic Mice.
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Academic Article
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Distinguishing Features of High- and Low-Dose Vaccine against Ocular HSV-1 Infection Correlates with Recognition of Specific HSV-1-Encoded Proteins.
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Academic Article
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Unforeseen consequences of IL-12 expression in the eye of GFAP-IL12 transgenic mice following herpes simplex virus type 1 infection.
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Academic Article
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The antiviral efficacy of the murine alpha-1 interferon transgene against ocular herpes simplex virus type 1 requires the presence of CD4(+), alpha/beta T-cell receptor-positive T lymphocytes with the capacity to produce gamma interferon.
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Academic Article
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Transient transfection of mouse fibroblasts with type I interferon transgenes provides various degrees of protection against herpes simplex virus infection.
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Academic Article
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Effect of anti-CXCL10 monoclonal antibody on herpes simplex virus type 1 keratitis and retinal infection.
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Academic Article
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The murine double-stranded RNA-dependent protein kinase PKR and the murine 2',5'-oligoadenylate synthetase-dependent RNase L are required for IFN-beta-mediated resistance against herpes simplex virus type 1 in primary trigeminal ganglion culture.
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Academic Article
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Interferon-beta suppresses herpes simplex virus type 1 replication in trigeminal ganglion cells through an RNase L-dependent pathway.
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Academic Article
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Consequences of CXCL10 and IL-6 induction by the murine IFN-alpha1 transgene in ocular herpes simplex virus type 1 infection.
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Academic Article
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ICP0 antagonizes Stat 1-dependent repression of herpes simplex virus: implications for the regulation of viral latency.
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Academic Article
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Susceptibility of CCR5-deficient mice to genital herpes simplex virus type 2 is linked to NK cell mobilization.
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Academic Article
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CD4+ T cell migration into the cornea is reduced in CXCL9 deficient but not CXCL10 deficient mice following herpes simplex virus type 1 infection.
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Academic Article
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Chemical sympathectomy increases susceptibility to ocular herpes simplex virus type 1 infection.
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Academic Article
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Lymphoid precursors are directed to produce dendritic cells as a result of TLR9 ligation during herpes infection.
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Academic Article
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CXCR3 deficiency increases susceptibility to genital herpes simplex virus type 2 infection: Uncoupling of CD8+ T-cell effector function but not migration.
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Academic Article
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PD-L1-expressing dendritic cells contribute to viral resistance during acute HSV-1 infection.
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Academic Article
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Comparison of the host immune response to herpes simplex virus 1 (HSV-1) and HSV-2 at two different mucosal sites.
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Academic Article
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Interferon-e protects the female reproductive tract from viral and bacterial infection.
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Academic Article
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Enhanced resistance of CXCR3 deficient mice to ocular HSV-1 infection is due to control of replication in the brain ependyma.
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Academic Article
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Caveolin-1 increases proinflammatory chemoattractants and blood-retinal barrier breakdown but decreases leukocyte recruitment in inflammation.
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Academic Article
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Degeneration and regeneration of corneal nerves in response to HSV-1 infection.
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Academic Article
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Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.
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Academic Article
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Corneal Epithelial Cells Exhibit Myeloid Characteristics and Present Antigen via MHC Class II.
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Academic Article
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Neuroretinal-Derived Caveolin-1 Promotes Endotoxin-Induced Inflammation in the Murine Retina.
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Academic Article
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Absence of PKR attenuates the anti-HSV-1 activity of an adenoviral vector expressing murine IFN-beta.
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Academic Article
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Resistance to ocular herpes simplex virus type 1 infection in IL-12 transgenic mice.
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Academic Article
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Distinctive roles for 2',5'-oligoadenylate synthetases and double-stranded RNA-dependent protein kinase R in the in vivo antiviral effect of an adenoviral vector expressing murine IFN-beta.
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Academic Article
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RNA-dependent protein kinase is required for alpha-1 interferon transgene-induced resistance to genital herpes simplex virus type 2.
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Academic Article
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Critical role for the oligoadenylate synthetase/RNase L pathway in response to IFN-beta during acute ocular herpes simplex virus type 1 infection.
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Academic Article
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Intact TRL 9 and type I interferon signaling pathways are required to augment HSV-1 induced corneal CXCL9 and CXCL10.
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Academic Article
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The lack of RNA-dependent protein kinase enhances susceptibility of mice to genital herpes simplex virus type 2 infection.
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Academic Article
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Oligoadenylate synthetase/protein kinase R pathways and alphabeta TCR+ T cells are required for adenovirus vector: IFN-gamma inhibition of herpes simplex virus-1 in cornea.
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Academic Article
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CXCL9 and CXCL10 expression are critical for control of genital herpes simplex virus type 2 infection through mobilization of HSV-specific CTL and NK cells to the nervous system.
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Academic Article
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Herpes simplex virus type 2-induced mortality following genital infection is blocked by anti-tumor necrosis factor alpha antibody in CXCL10-deficient mice.
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Academic Article
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Loss of mandibular lymph node integrity is associated with an increase in sensitivity to HSV-1 infection in CD118-deficient mice.
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Academic Article
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CD8+ T cells suppress viral replication in the cornea but contribute to VEGF-C-induced lymphatic vessel genesis.
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Academic Article
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HSV-1 targets lymphatic vessels in the eye and draining lymph node of mice leading to edema in the absence of a functional type I interferon response.
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Academic Article
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Microglia-induced IL-6 protects against neuronal loss following HSV-1 infection of neural progenitor cells.
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Academic Article
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A Highly Efficacious Herpes Simplex Virus 1 Vaccine Blocks Viral Pathogenesis and Prevents Corneal Immunopathology via Humoral Immunity.
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Academic Article
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IL-6 Contributes to Corneal Nerve Degeneration after Herpes Simplex Virus Type I Infection.
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Academic Article
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Herpesvirus-Associated Lymphadenitis Distorts Fibroblastic Reticular Cell Microarchitecture and Attenuates CD8 T Cell Responses to Neurotropic Infection in Mice Lacking the STING-IFNa/ß Defense Pathways.
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Academic Article
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Fibroblast growth factor-2 drives and maintains progressive corneal neovascularization following HSV-1 infection.
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Academic Article
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The Neonatal Fc Receptor and Complement Fixation Facilitate Prophylactic Vaccine-Mediated Humoral Protection against Viral Infection in the Ocular Mucosa.
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Academic Article
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Loss of Osteopontin Expression Reduces HSV-1-Induced Corneal Opacity.
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Grant
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The Role of CXCL9 in Genital HSV-2 Infection
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Grant
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NEUROIMMUNOLOGY OF HSV-1 REACTIVATION
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Grant
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The Neuroimmunology of Viral Infection
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Grant
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NEUROIMMUNOLOGY OF AED IN OCULAR HSV-1 INFECTION
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Grant
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Ocular Lymphangiogenesis
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Academic Article
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Lack of neonatal Fc receptor does not diminish the efficacy of the HSV-1 0?NLS vaccine against ocular HSV-1 challenge.
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Academic Article
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An intact complement system dampens cornea inflammation during acute primary HSV-1 infection.
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Academic Article
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The Chx10-Traf3 Knockout Mouse as a Viable Model to Study Neuronal Immune Regulation.
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Academic Article
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Tripartite-Motif 21 (TRIM21) Deficiency Results in a Modest Loss of Herpes Simplex Virus (HSV)-1 Surveillance in the Trigeminal Ganglia Following Cornea Infection.
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Academic Article
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Noncognate Signals Drive Enhanced Effector CD8+ T Cell Responses through an IFNAR1-Dependent Pathway after Infection with the Prototypic Vaccine, 0?NLS, against Herpes Simplex Virus 1.
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Academic Article
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HSV-1 0?NLS vaccine elicits a robust B lymphocyte response and preserves vision without HSV-1 glycoprotein M or thymidine kinase recognition.
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Academic Article
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Osteopontin contributes to virus resistance associated with type I IFN expression, activation of downstream ifn-inducible effector genes, and CCR2+CD115+CD206+ macrophage infiltration following ocular HSV-1 infection of mice.
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