"Retinal Degeneration" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)
| Descriptor ID |
D012162
|
| MeSH Number(s) |
C11.768.585
|
| Concept/Terms |
Retinal Degeneration- Retinal Degeneration
- Degeneration, Retinal
- Degenerations, Retinal
- Retinal Degenerations
|
Below are MeSH descriptors whose meaning is more general than "Retinal Degeneration".
Below are MeSH descriptors whose meaning is more specific than "Retinal Degeneration".
This graph shows the total number of publications written about "Retinal Degeneration" by people in this website by year, and whether "Retinal Degeneration" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 2 | 0 | 2 |
| 2004 | 2 | 0 | 2 |
| 2005 | 5 | 0 | 5 |
| 2006 | 2 | 0 | 2 |
| 2007 | 4 | 0 | 4 |
| 2008 | 2 | 1 | 3 |
| 2009 | 3 | 0 | 3 |
| 2010 | 6 | 3 | 9 |
| 2011 | 4 | 1 | 5 |
| 2012 | 6 | 0 | 6 |
| 2013 | 6 | 1 | 7 |
| 2014 | 6 | 1 | 7 |
| 2015 | 1 | 1 | 2 |
| 2016 | 5 | 0 | 5 |
| 2017 | 3 | 0 | 3 |
| 2018 | 4 | 0 | 4 |
| 2019 | 2 | 2 | 4 |
| 2020 | 5 | 0 | 5 |
| 2022 | 2 | 0 | 2 |
| 2023 | 6 | 0 | 6 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Retinal Degeneration" by people in Profiles.
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Age-related retinal degeneration resulting from the deletion of Shp2 tyrosine phosphatase in photoreceptor neurons. Cell Death Dis. 2024 Aug 08; 15(8):577.
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Transcriptomic Analysis Reveals That Excessive Thyroid Hormone Signaling Impairs Phototransduction and Mitochondrial Bioenergetics and Induces Cellular Stress in Mouse Cone Photoreceptors. Int J Mol Sci. 2024 Jul 06; 25(13).
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Interleukin-17-mediated protective cytokine signaling against degeneration of the retinal pigment epithelium. Proc Natl Acad Sci U S A. 2023 Dec 19; 120(51):e2311647120.
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Excessive Thyroid Hormone Signaling Induces Photoreceptor Degeneration in Mice. eNeuro. 2023 09; 10(9).
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Comparative study of PRPH2 D2 loop mutants reveals divergent disease mechanism in rods and cones. Cell Mol Life Sci. 2023 Jul 19; 80(8):214.
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A Dhdds K42E knock-in RP59 mouse model shows inner retina pathology and defective synaptic transmission. Cell Death Dis. 2023 Jul 13; 14(7):420.
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cGMP Signaling in Photoreceptor Degeneration. Int J Mol Sci. 2023 Jul 07; 24(13).
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Role of the ABCA4 Gene Expression in the Clearance of Toxic Vitamin A Derivatives in Human Hair Follicle Stem Cells and Keratinocytes. Int J Mol Sci. 2023 May 05; 24(9).
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Insulin-like growth factor 1 receptor mediates photoreceptor neuroprotection. Cell Death Dis. 2022 Jul 15; 13(7):613.
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Deuterated docosahexaenoic acid protects against oxidative stress and geographic atrophy-like retinal degeneration in a mouse model with iron overload. Aging Cell. 2022 04; 21(4):e13579.