"Retinal Degeneration" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)
| Descriptor ID |
D012162
|
| MeSH Number(s) |
C11.768.585
|
| Concept/Terms |
Retinal Degeneration- Retinal Degeneration
- Degeneration, Retinal
- Degenerations, Retinal
- Retinal Degenerations
|
Below are MeSH descriptors whose meaning is more general than "Retinal Degeneration".
Below are MeSH descriptors whose meaning is more specific than "Retinal Degeneration".
This graph shows the total number of publications written about "Retinal Degeneration" by people in this website by year, and whether "Retinal Degeneration" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2002 | 2 | 0 | 2 |
| 2003 | 2 | 0 | 2 |
| 2004 | 2 | 0 | 2 |
| 2005 | 5 | 0 | 5 |
| 2006 | 2 | 0 | 2 |
| 2007 | 4 | 0 | 4 |
| 2008 | 2 | 1 | 3 |
| 2009 | 3 | 0 | 3 |
| 2010 | 6 | 3 | 9 |
| 2011 | 5 | 1 | 6 |
| 2012 | 7 | 0 | 7 |
| 2013 | 6 | 1 | 7 |
| 2014 | 7 | 1 | 8 |
| 2015 | 2 | 1 | 3 |
| 2016 | 5 | 0 | 5 |
| 2017 | 3 | 0 | 3 |
| 2018 | 4 | 0 | 4 |
| 2019 | 2 | 2 | 4 |
| 2020 | 5 | 1 | 6 |
| 2022 | 2 | 0 | 2 |
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Below are the most recent publications written about "Retinal Degeneration" by people in Profiles.
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Insulin-like growth factor 1 receptor mediates photoreceptor neuroprotection. Cell Death Dis. 2022 Jul 15; 13(7):613.
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Deuterated docosahexaenoic acid protects against oxidative stress and geographic atrophy-like retinal degeneration in a mouse model with iron overload. Aging Cell. 2022 04; 21(4):e13579.
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Interphotoreceptor Retinol-Binding Protein Ameliorates Diabetes-Induced Retinal Dysfunction and Neurodegeneration Through Rhodopsin. Diabetes. 2021 03; 70(3):788-799.
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Retbindin: A riboflavin Binding Protein, Is Critical for Photoreceptor Homeostasis and Survival in Models of Retinal Degeneration. Int J Mol Sci. 2020 Oct 29; 21(21).
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Divergent Effects of HSP70 Overexpression in Photoreceptors During Inherited Retinal Degeneration. Invest Ophthalmol Vis Sci. 2020 10 01; 61(12):25.
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ROM1 contributes to phenotypic heterogeneity in PRPH2-associated retinal disease. Hum Mol Genet. 2020 09 29; 29(16):2708-2722.
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CRISPR/Cas9 mediated mutation of the mtnr1a melatonin receptor gene causes rod photoreceptor degeneration in developing Xenopus tropicalis. Sci Rep. 2020 08 13; 10(1):13757.
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The Elovl4 Spinocerebellar Ataxia-34 Mutation 736T>G (p.W246G) Impairs Retinal Function in the Absence of Photoreceptor Degeneration. Mol Neurobiol. 2020 Nov; 57(11):4735-4753.
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Potential contribution of ryanodine receptor 2 upregulation to cGMP/PKG signaling-induced cone degeneration in cyclic nucleotide-gated channel deficiency. FASEB J. 2020 05; 34(5):6335-6350.
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Copy-number variation contributes 9% of pathogenicity in the inherited retinal degenerations. Genet Med. 2020 06; 22(6):1079-1087.