"PC12 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CELL LINE derived from a PHEOCHROMOCYTOMA of the rat ADRENAL MEDULLA. PC12 cells stop dividing and undergo terminal differentiation when treated with NERVE GROWTH FACTOR, making the line a useful model system for NERVE CELL differentiation.
- PC12 Cells
- PC12 Cell
- Pheochromocytoma Cell Line
- Cell Line, Pheochromocytoma
- Cell Lines, Pheochromocytoma
- Pheochromocytoma Cell Lines
Below are MeSH descriptors whose meaning is more general than "PC12 Cells".
Below are MeSH descriptors whose meaning is more specific than "PC12 Cells".
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Below are the most recent publications written about "PC12 Cells" by people in Profiles.
A novel membrane targeting domain mediates the endosomal or Golgi localization specificity of small GTPases Rab22 and Rab31. J Biol Chem. 2022 09; 298(9):102281.
The Protein Tyrosine Phosphatase MEG2 Regulates the Transport and Signal Transduction of Tropomyosin Receptor Kinase A. J Biol Chem. 2016 Nov 11; 291(46):23895-23905.
Differential effects of overexpression of Rab5 and Rab22 on autophagy in PC12 cells with or without NGF. Methods Mol Biol. 2015; 1298:295-304.
Proteomic analysis of the mitochondria from embryonic and postnatal rat brains reveals response to developmental changes in energy demands. J Proteomics. 2014 Sep 23; 109:228-39.
ELOVL4 protein preferentially elongates 20:5n3 to very long chain PUFAs over 20:4n6 and 22:6n3. J Lipid Res. 2012 Mar; 53(3):494-504.
Rab22 controls NGF signaling and neurite outgrowth in PC12 cells. Mol Biol Cell. 2011 Oct; 22(20):3853-60.
HID-1, a new component of the peptidergic signaling pathway. Genetics. 2011 Feb; 187(2):467-83.
Modification of single walled carbon nanotube surface chemistry to improve aqueous solubility and enhance cellular interactions. Langmuir. 2008 Nov 18; 24(22):13173-81.
Nerve growth factor-mediated neurite outgrowth via regulation of Rab5. Mol Biol Cell. 2007 Apr; 18(4):1375-84.
A microarray study of MPP+-treated PC12 Cells: Mechanisms of toxicity (MOT) analysis using bioinformatics tools. BMC Bioinformatics. 2005 Jul 15; 6 Suppl 2:S8.