"Activin Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Receptors for ACTIVINS are membrane protein kinases belonging to the family of PROTEIN-SERINE-THREONINE KINASES, thus also named activin receptor-like kinases (ALK's). Activin receptors also bind TRANSFORMING GROWTH FACTOR BETA. As those transmembrane receptors of the TGF-beta superfamily (RECEPTORS, TRANSFORMING GROWTH FACTOR BETA), ALK's consist of two different but related protein kinases, Type I and Type II. Activins initiate cellular signal transduction by first binding to the type II receptors (ACTIVIN RECEPTORS, TYPE II ) which then recruit and phosphorylate the type I receptors (ACTIVIN RECEPTORS, TYPE I ) with subsequent activation of the type I kinase activity.
| Descriptor ID |
D029404
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.062 D12.776.543.750.750.400.820.500
|
| Concept/Terms |
Activin Receptors- Activin Receptors
- Receptor, Activin
- Activin Receptor-Like Kinases
- Activin Receptor like Kinases
- Kinases, Activin Receptor-like
- Receptor-like Kinases, Activin
- Activin Receptor
- Activin Receptor-like Kinase
- Activin Receptor like Kinase
- Kinase, Activin Receptor-like
- Receptor-like Kinase, Activin
|
Below are MeSH descriptors whose meaning is more general than "Activin Receptors".
Below are MeSH descriptors whose meaning is more specific than "Activin Receptors".
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