Toll-Like Receptor 9

"Toll-Like Receptor 9" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A pattern recognition receptor that binds unmethylated CPG CLUSTERS. It mediates cellular responses to bacterial pathogens by distinguishing between self and bacterial DNA.

Descriptor ID	D051217
MeSH Number(s)	D12.776.260.750 D12.776.543.750.705.910.500.900
Concept/Terms	Toll-Like Receptor 9 Toll-Like Receptor 9 Toll Like Receptor 9 TLR9 Receptor Receptor, TLR9 TLR9 Protein CD289 Antigen Antigen, CD289

Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptor 9".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Toll-Like Receptor 9 [D12.776.260.750]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Pattern Recognition [D12.776.543.750.705.910]
Toll-Like Receptors [D12.776.543.750.705.910.500]
Toll-Like Receptor 9 [D12.776.543.750.705.910.500.900]

Below are MeSH descriptors whose meaning is related to "Toll-Like Receptor 9".

Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptor 9".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Toll-Like Receptor 9" by people in this website by year, and whether "Toll-Like Receptor 9" was a major or minor topic of these publications.

Bar chart showing 8 publications over 5 distinct years, with a maximum of 2 publications in 2003 and 2006 and 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	0	2	2
2006	2	0	2
2008	1	1	2
2013	0	1	1
2016	0	1	1

Below are the most recent publications written about "Toll-Like Receptor 9" by people in Profiles.

Ward JM, Ratliff ML, Dozmorov MG, Wiley G, Guthridge JM, Gaffney PM, James JA, Webb CF. Human effector B lymphocytes express ARID3a and secrete interferon alpha. J Autoimmun. 2016 Dec; 75:130-140.

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Marabelle A, Kohrt H, Sagiv-Barfi I, Ajami B, Axtell RC, Zhou G, Rajapaksa R, Green MR, Torchia J, Brody J, Luong R, Rosenblum MD, Steinman L, Levitsky HI, Tse V, Levy R. Depleting tumor-specific Tregs at a single site eradicates disseminated tumors. J Clin Invest. 2013 Jun; 123(6):2447-63.

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Peters AL, Plenge RM, Graham RR, Altshuler DM, Moser KL, Gaffney PM, Bishop GA. A novel polymorphism of the human CD40 receptor with enhanced function. Blood. 2008 Sep 01; 112(5):1863-71.

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Welner RS, Pelayo R, Nagai Y, Garrett KP, Wuest TR, Carr DJ, Borghesi LA, Farrar MA, Kincade PW. Lymphoid precursors are directed to produce dendritic cells as a result of TLR9 ligation during herpes infection. Blood. 2008 Nov 01; 112(9):3753-61.

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Wuest T, Austin BA, Uematsu S, Thapa M, Akira S, Carr DJ. Intact TRL 9 and type I interferon signaling pathways are required to augment HSV-1 induced corneal CXCL9 and CXCL10. J Neuroimmunol. 2006 Oct; 179(1-2):46-52.

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Merrell MA, Ilvesaro JM, Lehtonen N, Sorsa T, Gehrs B, Rosenthal E, Chen D, Shackley B, Harris KW, Selander KS. Toll-like receptor 9 agonists promote cellular invasion by increasing matrix metalloproteinase activity. Mol Cancer Res. 2006 Jul; 4(7):437-47.

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Klinman DM, Zeuner R, Yamada H, Gursel M, Currie D, Gursel I. Regulation of CpG-induced immune activation by suppressive oligodeoxynucleotides. Ann N Y Acad Sci. 2003 Dec; 1002:112-23.

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Gursel I, Gursel M, Yamada H, Ishii KJ, Takeshita F, Klinman DM. Repetitive elements in mammalian telomeres suppress bacterial DNA-induced immune activation. J Immunol. 2003 Aug 01; 171(3):1393-400.

View in: PubMed

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