"Fas Ligand Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS.
| Descriptor ID |
D053222
|
| MeSH Number(s) |
D12.644.276.374.750.249 D12.776.395.550.312 D12.776.467.374.750.249 D12.776.543.550.312 D23.529.374.750.249
|
| Concept/Terms |
Fas Ligand Protein- Fas Ligand Protein
- CD95L
- Fas Ligand (FasL)
- FasL Protein
- TNF Superfamily, Member 6
- CD178 Antigen
- Antigen, CD178
- Antigens, CD178
- Fas Ligand
- Tumor Necrosis Factor Ligand Superfamily Member 6
- CD178 Antigens
- CD95 Antigen Ligand
- CD95 Ligand
|
Below are MeSH descriptors whose meaning is more general than "Fas Ligand Protein".
Below are MeSH descriptors whose meaning is more specific than "Fas Ligand Protein".
This graph shows the total number of publications written about "Fas Ligand Protein" by people in this website by year, and whether "Fas Ligand Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2014 | 0 | 2 | 2 |
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Below are the most recent publications written about "Fas Ligand Protein" by people in Profiles.
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Proinflammatory adaptive cytokine and shed tumor necrosis factor receptor levels are elevated preceding systemic lupus erythematosus disease flare. Arthritis Rheumatol. 2014 Jul; 66(7):1888-99.
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Death receptor (DR4) haplotypes are associated with increased susceptibility of gallbladder carcinoma in north Indian population. PLoS One. 2014; 9(2):e90264.
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Critical role of CFTR-dependent lipid rafts in cigarette smoke-induced lung epithelial injury. Am J Physiol Lung Cell Mol Physiol. 2011 Jun; 300(6):L811-20.
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Induction of plasma (TRAIL), TNFR-2, Fas ligand, and plasma microparticles after human immunodeficiency virus type 1 (HIV-1) transmission: implications for HIV-1 vaccine design. J Virol. 2008 Aug; 82(15):7700-10.
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Activation of the Fas-FasL signaling pathway by MDA-7/IL-24 kills human ovarian cancer cells. Cancer Res. 2005 Apr 15; 65(8):3017-24.
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Novel negative regulator of expression in Fas ligand (CD178) cytoplasmic tail: evidence for translational regulation and against Fas ligand retention in secretory lysosomes. J Immunol. 2004 Oct 15; 173(8):5095-102.
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Listeria monocytogenes virulence proteins induce surface expression of Fas ligand on T lymphocytes. Mol Microbiol. 2004 Mar; 51(5):1483-92.
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CD95 rapidly clusters in cells of diverse origins. Cancer Biol Ther. 2003 Jul-Aug; 2(4):392-5.
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Transgenic mice with pigmented intraocular tumors: tissue of origin and treatment. Invest Ophthalmol Vis Sci. 1998 Dec; 39(13):2800-5.