Signaling Lymphocytic Activation Molecule Family
"Signaling Lymphocytic Activation Molecule Family" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Type-I membrane glycoproteins that are expressed primarily on the surface of CD4 or CD8-positive T-CELLS; NATURAL KILLER CELLS; and some populations of B CELLS. They are characterized by an N-terminal, extracellular IMMUNOGLOBULIN-LIKE DOMAIN and a membrane-proximal IMMUNOGLOBULIN C2-SET DOMAIN. SLAMF receptors typically signal through homophilic interactions and are important for mediating the immune response and immune cell differentiation.
| Descriptor ID |
D000071176
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| MeSH Number(s) |
D12.776.395.550.736 D12.776.543.550.746 D12.776.543.750.705.970
|
| Concept/Terms |
Signaling Lymphocytic Activation Molecule Family- Signaling Lymphocytic Activation Molecule Family
- Signaling Lymphocytic Activation Molecule Receptors
- SLAMF Receptors
- Signaling Lymphocytic Activation Molecule Family Receptors
- Signaling Lymphocytic Activation Molecules
- SLAM Family Receptors
|
Below are MeSH descriptors whose meaning is more general than "Signaling Lymphocytic Activation Molecule Family".
Below are MeSH descriptors whose meaning is more specific than "Signaling Lymphocytic Activation Molecule Family".
This graph shows the total number of publications written about "Signaling Lymphocytic Activation Molecule Family" by people in this website by year, and whether "Signaling Lymphocytic Activation Molecule Family" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Signaling Lymphocytic Activation Molecule Family" by people in Profiles.
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Liver environment and HCV replication affect human T-cell phenotype and expression of inhibitory receptors. Gastroenterology. 2014 Feb; 146(2):550-61.
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The Ras/MAPK pathway is required for generation of iNKT cells. PLoS One. 2011 May 10; 6(5):e19890.