Signaling Lymphocytic Activation Molecule Family Member 1
"Signaling Lymphocytic Activation Molecule Family Member 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 70-kDa SLAM family receptor that consists of an extracellular IMMUNOGLOBULIN-LIKE DOMAIN and an IMMUNOGLOBULIN C2-SET DOMAIN. It is expressed primarily by THYMOCYTES and activated T-LYMPHOCYTES, as well as by MACROPHAGES and DENDRITIC CELLS. It binds SLAMF1 receptors on other cells to mediate T-cell maturation and proliferation. It is also a receptor for the MEASLES VIRUS.
| Descriptor ID |
D000071177
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| MeSH Number(s) |
D12.776.395.550.736.500 D12.776.543.550.746.500 D12.776.543.750.705.970.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Signaling Lymphocytic Activation Molecule Family Member 1".
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This graph shows the total number of publications written about "Signaling Lymphocytic Activation Molecule Family Member 1" by people in this website by year, and whether "Signaling Lymphocytic Activation Molecule Family Member 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 2 | 2 |
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Below are the most recent publications written about "Signaling Lymphocytic Activation Molecule Family Member 1" by people in Profiles.
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Control of early stages in invariant natural killer T-cell development. Immunology. 2011 Sep; 134(1):1-7.
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The Ras/MAPK pathway is required for generation of iNKT cells. PLoS One. 2011 May 10; 6(5):e19890.