"OX40 Ligand" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A membrane-bound tumor necrosis family member that is expressed on activated antigen-presenting cells such as B-LYMPHOCYTES and MACROPHAGES. It signals T-LYMPHOCYTES by binding the OX40 RECEPTOR.
| Descriptor ID |
D053278
|
| MeSH Number(s) |
D12.644.276.374.750.531 D12.776.395.550.597 D12.776.467.374.750.531 D12.776.543.550.590 D23.529.374.750.531
|
| Concept/Terms |
OX40 Ligand- OX40 Ligand
- CD134L Protein
- Tumor Necrosis Factor Ligand Superfamily Member 4
- OX40L Protein
- TNF Superfamily, Member 4
- Tumor Necrosis Factor (Ligand) Superfamily, Member 4
- CD134 Ligand
- gp34 Tumor Necrosis Factor
|
Below are MeSH descriptors whose meaning is more general than "OX40 Ligand".
Below are MeSH descriptors whose meaning is more specific than "OX40 Ligand".
This graph shows the total number of publications written about "OX40 Ligand" by people in this website by year, and whether "OX40 Ligand" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "OX40 Ligand" by people in Profiles.
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Anti-CD73 and anti-OX40 immunotherapy coupled with a novel biocompatible enzyme prodrug system for the treatment of recurrent, metastatic ovarian cancer. Cancer Lett. 2018 07 01; 425:174-182.
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Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans. Arthritis Rheumatol. 2016 05; 68(5):1197-1209.
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Analysis of a Genetic Polymorphism in the Costimulatory Molecule TNFSF4 with Hematopoietic Stem Cell Transplant Outcomes. Biol Blood Marrow Transplant. 2016 Jan; 22(1):27-36.
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Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4. PLoS Genet. 2013; 9(7):e1003554.
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Gene-gene interaction of BLK, TNFSF4, TRAF1, TNFAIP3, and REL in systemic lupus erythematosus. Arthritis Rheum. 2012 Jan; 64(1):222-31.
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A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap. PLoS Genet. 2011 Dec; 7(12):e1002406.
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Genetically determined Amerindian ancestry correlates with increased frequency of risk alleles for systemic lupus erythematosus. Arthritis Rheum. 2010 Dec; 62(12):3722-9.
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Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus. Nat Genet. 2008 Jan; 40(1):83-9.