CARD Signaling Adaptor Proteins
"CARD Signaling Adaptor Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of intracellular signaling adaptor proteins that contain CASPASE ACTIVATION AND RECRUITMENT DOMAINS (CARD). They play a role in APOPTOSIS-related signal transduction by associating with other CARD domain-containing members and activating INITIATOR CASPASES that contain CARD domains within their N-terminal pro-domain region.
Below are MeSH descriptors whose meaning is more general than "CARD Signaling Adaptor Proteins".
Below are MeSH descriptors whose meaning is more specific than "CARD Signaling Adaptor Proteins".
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Below are the most recent publications written about "CARD Signaling Adaptor Proteins" by people in Profiles.
Inflammasome Adaptor ASC Suppresses Apoptosis of Gastric Cancer Cells by an IL18-Mediated Inflammation-Independent Mechanism. Cancer Res. 2018 03 01; 78(5):1293-1307.
The Hepatitis C Virus-induced NLRP3 Inflammasome Activates the Sterol Regulatory Element-binding Protein (SREBP) and Regulates Lipid Metabolism. J Biol Chem. 2016 Feb 12; 291(7):3254-67.
Dectin-1 Activation by a Natural Product ß-Glucan Converts Immunosuppressive Macrophages into an M1-like Phenotype. J Immunol. 2015 Nov 15; 195(10):5055-65.