"3T3-L1 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A continuous cell line that is a substrain of SWISS 3T3 CELLS developed though clonal isolation. The mouse fibroblast cells undergo an adipose-like conversion as they move to a confluent and contact-inhibited state.
| Descriptor ID |
D041721
|
| MeSH Number(s) |
A11.251.210.100.775.800 A11.329.228.100.775.800
|
| Concept/Terms |
3T3-L1 Cells- 3T3-L1 Cells
- 3T3 L1 Cells
- 3T3-L1 Cell
- Cell, 3T3-L1
- Cells, 3T3-L1
|
Below are MeSH descriptors whose meaning is more general than "3T3-L1 Cells".
Below are MeSH descriptors whose meaning is more specific than "3T3-L1 Cells".
This graph shows the total number of publications written about "3T3-L1 Cells" by people in this website by year, and whether "3T3-L1 Cells" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2017 | 0 | 2 | 2 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 2 | 2 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "3T3-L1 Cells" by people in Profiles.
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Wu D, Eeda V, Undi RB, Mann S, Stout M, Lim HY, Wang W. A novel peroxisome proliferator-activated receptor gamma ligand improves insulin sensitivity and promotes browning of white adipose tissue in obese mice. Mol Metab. 2021 12; 54:101363.
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Griesel BA, Matsuzaki S, Batushansky A, Griffin TM, Humphries KM, Olson AL. PFKFB3-dependent glucose metabolism regulates 3T3-L1 adipocyte development. FASEB J. 2021 07; 35(7):e21728.
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Sparling DP, McCullough N, Pajvani U, Humphrey MB. Inhibition of ?-secretase in adipocytes leads to altered IL-6 secretion and adipose inflammation. Adipocyte. 2020 12; 9(1):325-334.
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Li B, Po SS, Zhang B, Bai F, Li J, Qin F, Liu N, Sun C, Xiao Y, Tu T, Zhou S, Liu Q. Metformin regulates adiponectin signalling in epicardial adipose tissue and reduces atrial fibrillation vulnerability. J Cell Mol Med. 2020 07; 24(14):7751-7766.
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Tryggestad JB, Teague AM, Sparling DP, Jiang S, Chernausek SD. Macrophage-Derived microRNA-155 Increases in Obesity and Influences Adipocyte Metabolism by Targeting Peroxisome Proliferator-Activated Receptor Gamma. Obesity (Silver Spring). 2019 11; 27(11):1856-1864.
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Olson AL. RalA signaling may reveal the true nature of 3T3-L1 adipocytes as a model for thermogenic adipocytes. Proc Natl Acad Sci U S A. 2018 07 24; 115(30):7651-7653.
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Jackson RM, Griesel BA, Gurley JM, Szweda LI, Olson AL. Glucose availability controls adipogenesis in mouse 3T3-L1 adipocytes via up-regulation of nicotinamide metabolism. J Biol Chem. 2017 11 10; 292(45):18556-18564.
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Li J, Chen C, Li Y, Matye DJ, Wang Y, Ding WX, Li T. Inhibition of insulin/PI3K/AKT signaling decreases adipose Sortilin 1 in mice and 3T3-L1 adipocytes. Biochim Biophys Acta Mol Basis Dis. 2017 11; 1863(11):2924-2933.
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Rahman SM, Janssen RC, Choudhury M, Baquero KC, Aikens RM, de la Houssaye BA, Friedman JE. CCAAT/enhancer-binding protein ß (C/EBPß) expression regulates dietary-induced inflammation in macrophages and adipose tissue in mice. J Biol Chem. 2012 Oct 05; 287(41):34349-60.
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Weems JC, Griesel BA, Olson AL. Class II histone deacetylases downregulate GLUT4 transcription in response to increased cAMP signaling in cultured adipocytes and fasting mice. Diabetes. 2012 Jun; 61(6):1404-14.