"3T3-L1 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A continuous cell line that is a substrain of SWISS 3T3 CELLS developed though clonal isolation. The mouse fibroblast cells undergo an adipose-like conversion as they move to a confluent and contact-inhibited state.
| Descriptor ID |
D041721
|
| MeSH Number(s) |
A11.251.210.100.775.800 A11.329.228.100.775.800
|
| Concept/Terms |
3T3-L1 Cells- 3T3-L1 Cells
- 3T3 L1 Cells
- 3T3-L1 Cell
- Cell, 3T3-L1
- Cells, 3T3-L1
|
Below are MeSH descriptors whose meaning is more general than "3T3-L1 Cells".
Below are MeSH descriptors whose meaning is more specific than "3T3-L1 Cells".
This graph shows the total number of publications written about "3T3-L1 Cells" by people in this website by year, and whether "3T3-L1 Cells" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 2 | 2 |
| 2020 | 0 | 2 | 2 |
| 2021 | 0 | 2 | 2 |
| 2025 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "3T3-L1 Cells" by people in Profiles.
-
Dietary oleic acid drives obesogenic adipogenesis via modulation of LXRa signaling. Cell Rep. 2025 Apr 22; 44(4):115527.
-
A novel peroxisome proliferator-activated receptor gamma ligand improves insulin sensitivity and promotes browning of white adipose tissue in obese mice. Mol Metab. 2021 12; 54:101363.
-
PFKFB3-dependent glucose metabolism regulates 3T3-L1 adipocyte development. FASEB J. 2021 07; 35(7):e21728.
-
Inhibition of ?-secretase in adipocytes leads to altered IL-6 secretion and adipose inflammation. Adipocyte. 2020 12; 9(1):325-334.
-
Metformin regulates adiponectin signalling in epicardial adipose tissue and reduces atrial fibrillation vulnerability. J Cell Mol Med. 2020 07; 24(14):7751-7766.
-
Macrophage-Derived microRNA-155 Increases in Obesity and Influences Adipocyte Metabolism by Targeting Peroxisome Proliferator-Activated Receptor Gamma. Obesity (Silver Spring). 2019 11; 27(11):1856-1864.
-
Molecular and Physiological Evaluation of Pancreatic Cancer-Induced Cachexia. Methods Mol Biol. 2019; 1882:321-333.
-
RalA signaling may reveal the true nature of 3T3-L1 adipocytes as a model for thermogenic adipocytes. Proc Natl Acad Sci U S A. 2018 07 24; 115(30):7651-7653.
-
Glucose availability controls adipogenesis in mouse 3T3-L1 adipocytes via up-regulation of nicotinamide metabolism. J Biol Chem. 2017 11 10; 292(45):18556-18564.
-
Inhibition of insulin/PI3K/AKT signaling decreases adipose Sortilin 1 in mice and 3T3-L1 adipocytes. Biochim Biophys Acta Mol Basis Dis. 2017 11; 1863(11):2924-2933.