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Aditya Dilip Joshi

InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentPharmaceutical Sciences
AddressCPB 331
1110 N Stonewall Ave
Oklahoma City OK 73117
Phone405/271-6593 ext 47471
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    Collapse Research 
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    R01DK122028     (JOSHI, ADITYA D)Jul 12, 2019 - Apr 30, 2024
    Novel mechanism of aryl hydrocarbon receptor - mediated differential gene regulation
    Role: Principal Investigator

    K01DK102514     (JOSHI, ADITYA)Sep 18, 2015 - Jun 30, 2019
    Characterization of cinnabarinic acid mediated cytoprotection upon liver injury
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Patil NY, Friedman JE, Joshi AD. Role of Hepatic Aryl Hydrocarbon Receptor in Non-Alcoholic Fatty Liver Disease. Receptors (Basel). 2023 Mar; 2(1):1-15. PMID: 37284280; PMCID: PMC10240927.
    2. Patil NY, Rus I, Downing E, Mandala A, Friedman JE, Joshi AD. Cinnabarinic Acid Provides Hepatoprotection Against Nonalcoholic Fatty Liver Disease. J Pharmacol Exp Ther. 2022 10; 383(1):32-43. PMID: 35933113; PMCID: PMC9513857.
      Citations: 2     Fields:    Translation:HumansAnimals
    3. Joshi AD, Thinakaran G, Elferink C. Cinnabarinic Acid-Induced Stanniocalcin 2 Confers Cytoprotection against Alcohol-Induced Liver Injury. J Pharmacol Exp Ther. 2022 Apr; 381(1):1-11. PMID: 35078862.
      Citations: 3     Fields:    Translation:Animals
    4. Patil NY, Tang H, Rus I, Zhang K, Joshi AD. Decoding Cinnabarinic Acid-Specific Stanniocalcin 2 Induction by Aryl Hydrocarbon Receptor. Mol Pharmacol. 2022 01; 101(1):45-55. PMID: 34764210.
      Citations: 3     Fields:    Translation:AnimalsCells
    5. Girer NG, Rontoyanni VG, Joshi A, Patrikeev I, Murton AJ, Porter C, Motamedi M, Elferink CJ. Liver-Specific Nonviral Gene Delivery of Fibroblast Growth Factor 21 Protein Expression in Mice Regulates Body Mass and White/Brown Fat Respiration. J Pharmacol Exp Ther. 2021 08; 378(2):157-165. PMID: 34074713.
      Citations: 2     Fields:    Translation:AnimalsCells
    6. Joshi AD. New Insights Into Physiological and Pathophysiological Functions of Stanniocalcin 2. Front Endocrinol (Lausanne). 2020; 11:172. PMID: 32296395.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    7. Joshi AD, Hossain E, Elferink CJ. Epigenetic Regulation by Agonist-Specific Aryl Hydrocarbon Receptor Recruitment of Metastasis-Associated Protein 2 Selectively Induces Stanniocalcin 2 Expression. Mol Pharmacol. 2017 09; 92(3):366-374. PMID: 28696214.
      Citations: 11     Fields:    Translation:AnimalsCells
    8. Lee CS, Hanna AD, Wang H, Dagnino-Acosta A, Joshi AD, Knoblauch M, Xia Y, Georgiou DK, Xu J, Long C, Amano H, Reynolds C, Dong K, Martin JC, Lagor WR, Rodney GG, Sahin E, Sewry C, Hamilton SL. A chemical chaperone improves muscle function in mice with a RyR1 mutation. Nat Commun. 2017 03 24; 8:14659. PMID: 28337975.
      Citations: 39     Fields:    Translation:AnimalsCells
    9. Wright EJ, De Castro KP, Joshi AD, Elferink CJ. Canonical and non-canonical aryl hydrocarbon receptor signaling pathways. Curr Opin Toxicol. 2017 Feb; 2:87-92. PMID: 32296737.
      Citations: 37     
    10. Gaziova I, Jackson D, Boor PJ, Carter D, Cruz-Monserrate Z, Elferink CJ, Joshi AD, Kaphalia B, Logsdon CD, Pereira de Castro K, Soong L, Tao X, Qiu S, Elferink LA. The MET Receptor Tyrosine Kinase Confers Repair of Murine Pancreatic Acinar Cells following Acute and Chronic Injury. PLoS One. 2016; 11(10):e0165485. PMID: 27798657.
      Citations:    Fields:    Translation:HumansAnimalsCells
    11. Joshi AD, Mustafa MG, Lichti CF, Elferink CJ. Homocitrullination Is a Novel Histone H1 Epigenetic Mark Dependent on Aryl Hydrocarbon Receptor Recruitment of Carbamoyl Phosphate Synthase 1. J Biol Chem. 2015 Nov 13; 290(46):27767-78. PMID: 26424795.
      Citations: 14     Fields:    Translation:AnimalsCells
    12. Joshi AD, Carter DE, Harper TA, Elferink CJ. Aryl hydrocarbon receptor-dependent stanniocalcin 2 induction by cinnabarinic acid provides cytoprotection against endoplasmic reticulum and oxidative stress. J Pharmacol Exp Ther. 2015 Apr; 353(1):201-12. PMID: 25672339.
      Citations: 21     Fields:    Translation:AnimalsCells
    13. Lee CS, Georgiou DK, Dagnino-Acosta A, Xu J, Ismailov II, Knoblauch M, Monroe TO, Ji R, Hanna AD, Joshi AD, Long C, Oakes J, Tran T, Corona BT, Lorca S, Ingalls CP, Narkar VA, Lanner JT, Bayle JH, Durham WJ, Hamilton SL. Ligands for FKBP12 increase Ca2+ influx and protein synthesis to improve skeletal muscle function. J Biol Chem. 2014 Sep 12; 289(37):25556-70. PMID: 25053409.
      Citations: 10     Fields:    Translation:AnimalsCells
    14. Jackson DP, Li H, Mitchell KA, Joshi AD, Elferink CJ. Ah receptor-mediated suppression of liver regeneration through NC-XRE-driven p21Cip1 expression. Mol Pharmacol. 2014 Apr; 85(4):533-41. PMID: 24431146.
      Citations: 39     Fields:    Translation:AnimalsCells
    15. Wilson SR, Joshi AD, Elferink CJ. The tumor suppressor Kruppel-like factor 6 is a novel aryl hydrocarbon receptor DNA binding partner. J Pharmacol Exp Ther. 2013 Jun; 345(3):419-29. PMID: 23512538.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    16. Harper TA, Joshi AD, Elferink CJ. Identification of stanniocalcin 2 as a novel aryl hydrocarbon receptor target gene. J Pharmacol Exp Ther. 2013 Mar; 344(3):579-88. PMID: 23269473.
      Citations: 20     Fields:    Translation:AnimalsCells
    17. Lanner JT, Georgiou DK, Dagnino-Acosta A, Ainbinder A, Cheng Q, Joshi AD, Chen Z, Yarotskyy V, Oakes JM, Lee CS, Monroe TO, Santillan A, Dong K, Goodyear L, Ismailov II, Rodney GG, Dirksen RT, Hamilton SL. AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation. Nat Med. 2012 Jan 08; 18(2):244-51. PMID: 22231556.
      Citations: 61     Fields:    Translation:AnimalsCells
    18. Pajor AM, Sun NN, Joshi AD, Randolph KM. Transmembrane helix 7 in the Na+/dicarboxylate cotransporter 1 is an outer helix that contains residues critical for function. Biochim Biophys Acta. 2011 Jun; 1808(6):1454-61. PMID: 21073858.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    19. Lanner JT, Georgiou DK, Joshi AD, Hamilton SL. Ryanodine receptors: structure, expression, molecular details, and function in calcium release. Cold Spring Harb Perspect Biol. 2010 Nov; 2(11):a003996. PMID: 20961976.
      Citations: 328     Fields:    Translation:HumansAnimalsCells
    20. Joshi AD, Pajor AM. Identification of conformationally sensitive amino acids in the Na(+)/dicarboxylate symporter (SdcS). Biochemistry. 2009 Apr 07; 48(13):3017-24. PMID: 19260674.
      Citations: 4     Fields:    Translation:AnimalsCells
    21. Joshi AD, Pajor AM. Role of conserved prolines in the structure and function of the Na+/dicarboxylate cotransporter 1, NaDC1. Biochemistry. 2006 Apr 04; 45(13):4231-9. PMID: 16566597.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
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