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Checkpoint Kinase 1

"Checkpoint Kinase 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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A serine/threonine-specific protein kinase which is encoded by the CHEK1 gene in humans. Checkpoint kinase 1 (also known as Chk1) coordinates DNA damage response and cell cycle checkpoint response. Under these conditions, activation of Chk1 results in the initiation of cell cycle checkpoints, cell cycle arrest, DNA repair and cell death, to prevent damaged cells from progressing through the cell cycle.


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This graph shows the total number of publications written about "Checkpoint Kinase 1" by people in this website by year, and whether "Checkpoint Kinase 1" was a major or minor topic of these publications.
Bar chart showing 4 publications over 4 distinct years, with a maximum of 1 publications in 2004 and 2008 and 2018 and 2020
To see the data from this visualization as text, click here.