"Gene Editing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genetic engineering techniques that involve DNA REPAIR mechanisms for incorporating site-specific modifications into a cell's genome.
| Descriptor ID |
D000072669
|
| MeSH Number(s) |
E05.393.420.270
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Gene Editing".
Below are MeSH descriptors whose meaning is more specific than "Gene Editing".
This graph shows the total number of publications written about "Gene Editing" by people in this website by year, and whether "Gene Editing" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 3 | 4 |
| 2022 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Gene Editing" by people in Profiles.
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Differential Divalent Metal Binding by SpyCas9's RuvC Active Site Contributes to Nonspecific DNA Cleavage. CRISPR J. 2023 Dec; 6(6):527-542.
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Rational Engineering of CRISPR-Cas9 Nuclease to Attenuate Position-Dependent Off-Target Effects. CRISPR J. 2022 04; 5(2):329-340.
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Cas9 Nickase-Based Genome Editing in Clostridium cellulolyticum. Methods Mol Biol. 2022; 2479:227-243.
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The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race. J Physician Assist Educ. 2021 Dec 01; 32(4):266-267.
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Identification of ClpP Dual Isoform Disruption as an Antisporulation Strategy for Clostridioides difficile. J Bacteriol. 2022 02 15; 204(2):e0041121.
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The bridge helix of Cas12a imparts selectivity in cis-DNA cleavage and regulates trans-DNA cleavage. FEBS Lett. 2021 04; 595(7):892-912.
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The CRISPR-Cas Mechanism for Adaptive Immunity and Alternate Bacterial Functions Fuels Diverse Biotechnologies. Front Cell Infect Microbiol. 2020; 10:619763.
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Screening for functional transcriptional and splicing regulatory variants with GenIE. Nucleic Acids Res. 2020 12 16; 48(22):e131.
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Bridge Helix of Cas9 Modulates Target DNA Cleavage and Mismatch Tolerance. Biochemistry. 2019 04 09; 58(14):1905-1917.
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Switchable genome editing via genetic code expansion. Sci Rep. 2018 07 03; 8(1):10051.