Somatic Hypermutation, Immunoglobulin
"Somatic Hypermutation, Immunoglobulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A programmed mutation process whereby changes are introduced to the nucleotide sequence of immunoglobulin gene DNA during development.
Descriptor ID |
D027041
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MeSH Number(s) |
G05.558.810 G12.500.780
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Concept/Terms |
Somatic Hypermutation, Immunoglobulin- Somatic Hypermutation, Immunoglobulin
- Hypermutation, Immunoglobulin Somatic
- Hypermutations, Immunoglobulin Somatic
- Immunoglobulin Somatic Hypermutations
- Somatic Hypermutations, Immunoglobulin
- Ig Somatic Hypermutation
- Immunoglobulin Somatic Hypermutation
- Hypermutation, Somatic, Immunoglobulin
- Somatic Hypermutation, Ig
- Hypermutation, Ig Somatic
- Hypermutations, Ig Somatic
- Ig Somatic Hypermutations
- Somatic Hypermutations, Ig
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Below are MeSH descriptors whose meaning is more general than "Somatic Hypermutation, Immunoglobulin".
Below are MeSH descriptors whose meaning is more specific than "Somatic Hypermutation, Immunoglobulin".
This graph shows the total number of publications written about "Somatic Hypermutation, Immunoglobulin" by people in this website by year, and whether "Somatic Hypermutation, Immunoglobulin" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 0 | 1 | 1 |
2011 | 1 | 0 | 1 |
2018 | 1 | 0 | 1 |
2020 | 0 | 1 | 1 |
2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Somatic Hypermutation, Immunoglobulin" by people in Profiles.
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A Small Step, a Giant Leap: Somatic Hypermutation of a Single Amino Acid Leads to Anti-La Autoreactivity. Int J Mol Sci. 2021 Nov 07; 22(21).
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T Cell Mediated Conversion of a Non-Anti-La Reactive B Cell to an Autoreactive Anti-La B Cell by Somatic Hypermutation. Int J Mol Sci. 2021 Jan 26; 22(3).
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Human C. difficile toxin-specific memory B cell repertoires encode poorly neutralizing antibodies. JCI Insight. 2020 08 20; 5(16).
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Evidence of Alternative Modes of B Cell Activation Involving Acquired Fab Regions of N-Glycosylation in Antibody-Secreting Cells Infiltrating the Labial Salivary Glands of Patients With Sjögren's Syndrome. Arthritis Rheumatol. 2018 07; 70(7):1102-1113.
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Characterizing somatic hypermutation and gene conversion in the chicken DT40 cell system. Methods Mol Biol. 2011; 748:255-71.
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Rapid cloning of high-affinity human monoclonal antibodies against influenza virus. Nature. 2008 May 29; 453(7195):667-71.
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Cutting edge: a cis-acting DNA element targets AID-mediated sequence diversification to the chicken Ig light chain gene locus. J Immunol. 2008 Feb 15; 180(4):2019-23.