"Genes, Immunoglobulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes encoding the different subunits of the IMMUNOGLOBULINS, for example the IMMUNOGLOBULIN LIGHT CHAIN GENES and the IMMUNOGLOBULIN HEAVY CHAIN GENES. The heavy and light immunoglobulin genes are present as gene segments in the germline cells. The completed genes are created when the segments are shuffled and assembled (B-LYMPHOCYTE GENE REARRANGEMENT) during B-LYMPHOCYTE maturation. The gene segments of the human light and heavy chain germline genes are symbolized V (variable), J (joining) and C (constant). The heavy chain germline genes have an additional segment D (diversity).
| Descriptor ID |
D005803
|
| MeSH Number(s) |
G05.360.340.024.340.335 G12.500.299
|
| Concept/Terms |
Genes, Immunoglobulin- Genes, Immunoglobulin
- Immunoglobulin Genes
- Gene, Immunoglobulin
- Immunoglobulin Gene
- Genes, Ig
- Gene, Ig
- Ig Gene
- Ig Genes
|
Below are MeSH descriptors whose meaning is more general than "Genes, Immunoglobulin".
Below are MeSH descriptors whose meaning is more specific than "Genes, Immunoglobulin".
This graph shows the total number of publications written about "Genes, Immunoglobulin" by people in this website by year, and whether "Genes, Immunoglobulin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2011 | 3 | 0 | 3 |
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Below are the most recent publications written about "Genes, Immunoglobulin" by people in Profiles.
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Separation of mutational and transcriptional enhancers in Ig genes. J Immunol. 2011 Sep 15; 187(6):3247-55.
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Targeting of AID-mediated sequence diversification to immunoglobulin genes. Curr Opin Immunol. 2011 Apr; 23(2):184-9.
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Characterizing somatic hypermutation and gene conversion in the chicken DT40 cell system. Methods Mol Biol. 2011; 748:255-71.
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Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors. J Exp Med. 2009 Jan 16; 206(1):139-51.
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Induction of immunoglobulin heavy-chain transcription through the transcription factor Bright requires TFII-I. Mol Cell Biol. 2006 Jun; 26(12):4758-68.
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Cutaneous immunocytoma: a clinical, histologic, and phenotypic study of 11 cases. Appl Immunohistochem Mol Morphol. 2004 Sep; 12(3):216-24.
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Fatal acute lymphoblastic leukemia in mice transgenic for B cell-restricted bcl-xL and c-myc. J Immunol. 2004 Jun 01; 172(11):6684-91.
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Antibody epitopes on the neuraminidase of a recent H3N2 influenza virus (A/Memphis/31/98). J Virol. 2002 Dec; 76(23):12274-80.
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High frequency of matrix attachment regions and cut-like protein x/CCAAT-displacement protein and B cell regulator of IgH transcription binding sites flanking Ig V region genes. J Immunol. 2002 Sep 01; 169(5):2477-87.
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Relatively normal human lymphopoiesis but rapid turnover of newly formed B cells in transplanted nonobese diabetic/SCID mice. J Immunol. 2001 Sep 15; 167(6):3033-42.