Cyclin-Dependent Kinase 5
"Cyclin-Dependent Kinase 5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serine-threonine kinase that plays important roles in CELL DIFFERENTIATION; CELL MIGRATION; and CELL DEATH of NERVE CELLS. It is closely related to other CYCLIN-DEPENDENT KINASES but does not seem to participate in CELL CYCLE regulation.
| Descriptor ID |
D051360
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.646.500.500.500 D12.644.360.250.067.875 D12.776.167.200.067.875 D12.776.476.250.067.875
|
| Concept/Terms |
Cyclin-Dependent Kinase 5- Cyclin-Dependent Kinase 5
- Cyclin Dependent Kinase 5
- Neuronal Cdc2-Like Protein Kinase
- Neuronal Cdc2 Like Protein Kinase
- Cdk5 Protein Kinase
- Protein Kinase, Cdk5
- Cdk5 Protein
- PSSALRE Protein
- Cdc2-Related Kinase PSSALRE
- Cdc2 Related Kinase PSSALRE
- PSSALRE, Cdc2-Related Kinase
|
Below are MeSH descriptors whose meaning is more general than "Cyclin-Dependent Kinase 5".
Below are MeSH descriptors whose meaning is more specific than "Cyclin-Dependent Kinase 5".
This graph shows the total number of publications written about "Cyclin-Dependent Kinase 5" by people in this website by year, and whether "Cyclin-Dependent Kinase 5" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2015 | 1 | 1 | 2 |
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Below are the most recent publications written about "Cyclin-Dependent Kinase 5" by people in Profiles.
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UNC-16 (JIP3) Acts Through Synapse-Assembly Proteins to Inhibit the Active Transport of Cell Soma Organelles to Caenorhabditis elegans Motor Neuron Axons. Genetics. 2015 Sep; 201(1):117-41.
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Cell cycle-dependent ubiquitylation and destruction of NDE1 by CDK5-FBW7 regulates ciliary length. EMBO J. 2015 Oct 01; 34(19):2424-40.
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Cyclin-dependent kinase 5 is amplified and overexpressed in pancreatic cancer and activated by mutant K-Ras. Clin Cancer Res. 2011 Oct 01; 17(19):6140-50.
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When good Cdk5 turns bad. Sci Aging Knowledge Environ. 2006 Feb 08; 2006(5):pe5.
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Cyclin-dependent kinase 5--a neuronal killer? Sci Aging Knowledge Environ. 2003 Dec 17; 2003(50):pe36.