"RNA-Binding Protein FUS" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multifunctional heterogeneous-nuclear ribonucleoprotein that may play a role in homologous DNA pairing and recombination. The N-terminal portion of protein is a potent transcriptional activator, while the C terminus is required for RNA binding. The name FUS refers to the fact that genetic recombination events result in fusion oncogene proteins (ONCOGENE PROTEINS, FUSION) that contain the N-terminal region of this protein. These fusion proteins have been found in myxoid liposarcoma (LIPOSARCOMA, MYXOID) and acute myeloid leukemia.
| Descriptor ID |
D034702
|
| MeSH Number(s) |
D12.776.157.725.813.750.905 D12.776.624.664.700.915 D12.776.664.962.813.750.902
|
| Concept/Terms |
RNA-Binding Protein FUS- RNA-Binding Protein FUS
- RNA Binding Protein FUS
- TLS Protein
- POMp75 Protein
- Translocated in Liposarcoma Protein
- FUS RNA-Binding Protein
- FUS RNA Binding Protein
- RNA-Binding Protein, FUS
- Fusion Protein in Myxoid Liposarcoma
- FUS Protein
- hnRNP P2
|
Below are MeSH descriptors whose meaning is more general than "RNA-Binding Protein FUS".
Below are MeSH descriptors whose meaning is more specific than "RNA-Binding Protein FUS".
This graph shows the total number of publications written about "RNA-Binding Protein FUS" by people in this website by year, and whether "RNA-Binding Protein FUS" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "RNA-Binding Protein FUS" by people in Profiles.
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Plasma Tau and Neurofilament Light in Frontotemporal Lobar Degeneration and Alzheimer Disease. Neurology. 2021 02 02; 96(5):e671-e683.
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Nanoparticle based systemic gene therapy for lung cancer: molecular mechanisms and strategies to suppress nanoparticle-mediated inflammatory response. Technol Cancer Res Treat. 2004 Dec; 3(6):647-57.