"RNA-Binding Protein EWS" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitous hnRNP protein that contains an RNA RECOGNITION MOTIF and C-terminal ranBP2-type zinc finger. It localizes to the CELL NUCLEUS and CYTOPLASM and is expressed as different isoforms in various tissues, interacting with CALMODULIN and TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Translocations that result in the formation of fusion proteins containing parts of RNA-binding protein EWS are associated with EWING SARCOMA.
| Descriptor ID |
D034802
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| MeSH Number(s) |
D12.644.360.650 D12.776.157.142.750 D12.776.157.725.813.750.900 D12.776.476.650 D12.776.624.664.700.913 D12.776.664.962.813.750.900
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| Concept/Terms |
RNA-Binding Protein EWS- RNA-Binding Protein EWS
- EWS, RNA-Binding Protein
- RNA Binding Protein EWS
- EWSR1 Protein
- Protein, EWSR1
- Ewing Sarcoma Breakpoint Region 1 Protein
- EWS Proto-Oncogene Protein
- EWS Proto Oncogene Protein
- Proto-Oncogene Protein, EWS
- Ewing Sarcoma Breakpointregion 1 Protein
- EWS RNA Binding Protein 1
- EWS Protein
|
Below are MeSH descriptors whose meaning is more general than "RNA-Binding Protein EWS".
Below are MeSH descriptors whose meaning is more specific than "RNA-Binding Protein EWS".
This graph shows the total number of publications written about "RNA-Binding Protein EWS" by people in this website by year, and whether "RNA-Binding Protein EWS" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 1 | 2 |
| 2011 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "RNA-Binding Protein EWS" by people in Profiles.
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SIX1 and EWS/FLI1 co-regulate an anti-metastatic gene network in Ewing Sarcoma. Nat Commun. 2023 07 19; 14(1):4357.
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EWSR1-PATZ1-rearranged sarcoma: a report of nine cases of spindle and round cell neoplasms with predilection for thoracoabdominal soft tissues and frequent expression of neural and skeletal muscle markers. Mod Pathol. 2021 04; 34(4):770-785.
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Malignant Ewing-Like Neoplasm With an EWSR1-KLF15 Fusion: At the Crossroads of a Myoepithelial Carcinoma and a Ewing-Like Sarcoma. A Case Report With Treatment Options. Int J Surg Pathol. 2018 Aug; 26(5):440-447.
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Exenteration and Custom Implant Brachytherapy as a Treatment for Recurrent Primary Extraskeletal Orbital Ewing Sarcoma. Ophthalmic Plast Reconstr Surg. 2015 Jul-Aug; 31(4):e89-91.
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Extraosseous Ewing's sarcoma of the pancreas. Int J Clin Oncol. 2012 Aug; 17(4):399-406.
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EWS-ETS oncoproteins: the linchpins of Ewing tumors. Gene. 2005 Dec 19; 363:1-14.
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A 15-year-old female with progressive myelopathy. Brain Pathol. 2005 Jul; 15(3):265-7.
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Cytogenetic and molecular cytogenetic studies of a variant of t(21;22), ins(22;21)(q12;q21q22), with a deletion of the 3' EWSR1 gene in a patient with Ewing sarcoma. Cancer Genet Cytogenet. 2005 Jun; 159(2):177-80.
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Vascular endothelial growth factor expression is up-regulated by EWS-ETS oncoproteins and Sp1 and may represent an independent predictor of survival in Ewing's sarcoma. Clin Cancer Res. 2004 Feb 15; 10(4):1344-53.
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Upregulation of the matrix metalloproteinase-1 gene by the Ewing's sarcoma associated EWS-ER81 and EWS-Fli-1 oncoproteins, c-Jun and p300. FEBS Lett. 2003 Oct 09; 553(1-2):104-8.