"Mucin-4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transmembrane mucin that is found in a broad variety of epithelial tissue. Mucin-4 may play a role in regulating cellular adhesion and in cell surface signaling from the ERBB-2 RECEPTOR PROTEIN-TYROSINE KINASE. Mucin-4 is a heterodimer of alpha and beta chains. The alpha and beta chains result from the proteolytic cleavage of a precursor protein.
| Descriptor ID |
D055264
|
| MeSH Number(s) |
D12.644.360.534 D12.776.395.560.631.195 D12.776.476.534
|
| Concept/Terms |
Mucin-4 alpha chain- Mucin-4 alpha chain
- Mucin 4 alpha chain
- Ascites Sialoglycoprotein 1
- Sialoglycoprotein 1, Ascites
- ASGP-1
|
Below are MeSH descriptors whose meaning is more general than "Mucin-4".
Below are MeSH descriptors whose meaning is more specific than "Mucin-4".
This graph shows the total number of publications written about "Mucin-4" by people in this website by year, and whether "Mucin-4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mucin-4" by people in Profiles.
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Effects of High-Fat Diet on Carcinogen-Induced Pancreatic Cancer and Intestinal Microbiota in C57BL/6 Wild-Type Mice. Pancreas. 2021 04 01; 50(4):564-570.
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MUC4 mucin interacts with and stabilizes the HER2 oncoprotein in human pancreatic cancer cells. Cancer Res. 2008 Apr 01; 68(7):2065-70.