Autophagy-Related Protein 7
"Autophagy-Related Protein 7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autophagy related protein that is similar to UBIQUITIN-ACTIVATING ENZYME E1. It functions in CYTOPLASM to VACUOLE transport (Cvt) and AUTOPHAGY by activating ATG12 PROTEIN for its conjugation with ATG5 PROTEIN, as well as the conjugation of ATG8 FAMILY PROTEINS with phosphatidylethanolamine for ATG8 association to Cvt vesicles and AUTOPHAGOSOME membranes. It is also required for the nitrogen starvation response in yeast, MITOPHAGY; and autophagic cell death induced by CASPASE 8 inhibition.
| Descriptor ID |
D000071193
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| MeSH Number(s) |
D12.776.094.399
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| Concept/Terms |
Autophagy-Related Protein 7- Autophagy-Related Protein 7
- Autophagy Related Protein 7
- ATG7 Protein
- Ubiquitin-Activating Enzyme E1-like Protein
- Ubiquitin Activating Enzyme E1 like Protein
- Ubiquitin-Like Modifier-Activating Enzyme ATG7
- Ubiquitin Like Modifier Activating Enzyme ATG7
- ATG12-Activating Enzyme E1 ATG7
- ATG12 Activating Enzyme E1 ATG7
|
Below are MeSH descriptors whose meaning is more general than "Autophagy-Related Protein 7".
Below are MeSH descriptors whose meaning is more specific than "Autophagy-Related Protein 7".
This graph shows the total number of publications written about "Autophagy-Related Protein 7" by people in this website by year, and whether "Autophagy-Related Protein 7" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Autophagy-Related Protein 7" by people in Profiles.
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Early AMD-like defects in the RPE and retinal degeneration in aged mice with RPE-specific deletion of Atg5 or Atg7. Mol Vis. 2017; 23:228-241.
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Di-retinoid-pyridinium-ethanolamine (A2E) Accumulation and the Maintenance of the Visual Cycle Are Independent of Atg7-mediated Autophagy in the Retinal Pigmented Epithelium. J Biol Chem. 2015 Nov 27; 290(48):29035-44.
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Autophagy protects the retina from light-induced degeneration. J Biol Chem. 2013 Mar 15; 288(11):7506-7518.