Autophagy-Related Protein 5
"Autophagy-Related Protein 5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autophagy-related protein that functions in AUTOPHAGOSOME biogenesis. It is conjugated to the ATG12 PROTEIN via a process that is similar to UBIQUITINATION and involves the ATG7 PROTEIN and ATG10 enzyme. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme and is required for the localization of ATG8 PROTEINS to AUTOPHAGOSOME vesicle membranes and modification of membrane lipids.
| Descriptor ID |
D000071187
|
| MeSH Number(s) |
D12.776.094.250
|
| Concept/Terms |
Autophagy-Related Protein 5- Autophagy-Related Protein 5
- Autophagy Related Protein 5
- Apoptosis-Specific Protein
- Apoptosis Specific Protein
- ATG5 Protein
- ATG-5 Protein
- ATG 5 Protein
- Autophagy Protein-5
- Autophagy Protein 5
- Autophagy-Related 5 Protein
- Autophagy Related 5 Protein
|
Below are MeSH descriptors whose meaning is more general than "Autophagy-Related Protein 5".
Below are MeSH descriptors whose meaning is more specific than "Autophagy-Related Protein 5".
This graph shows the total number of publications written about "Autophagy-Related Protein 5" by people in this website by year, and whether "Autophagy-Related Protein 5" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Autophagy-Related Protein 5" by people in Profiles.
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Early AMD-like defects in the RPE and retinal degeneration in aged mice with RPE-specific deletion of Atg5 or Atg7. Mol Vis. 2017; 23:228-241.