"Aurora Kinase B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An aurora kinase that is a component of the chromosomal passenger protein complex and is involved in the regulation of MITOSIS. It mediates proper CHROMOSOME SEGREGATION and contractile ring function during CYTOKINESIS.
| Descriptor ID |
D064107
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.103.750 D12.776.167.049.750
|
| Concept/Terms |
Aurora Kinase B- Aurora Kinase B
- Serine-Threonine Protein Kinase 12
- Serine Threonine Protein Kinase 12
- Aurora-Related Kinase 2
- Aurora Related Kinase 2
- Aurora B Kinases
- Aurora Kinases B
|
Below are MeSH descriptors whose meaning is more general than "Aurora Kinase B".
Below are MeSH descriptors whose meaning is more specific than "Aurora Kinase B".
This graph shows the total number of publications written about "Aurora Kinase B" by people in this website by year, and whether "Aurora Kinase B" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Aurora Kinase B" by people in Profiles.
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The heterogeneous transition state of resistance to RET kinase inhibitors converges on ERK1/2-driven Aurora A/B kinases. Drug Resist Updat. 2023 May; 68:100958.
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PBAF chromatin remodeler complexes that mediate meiotic transitions in mouse. Development. 2022 09 15; 149(18).
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GTSE1 regulates spindle microtubule dynamics to control Aurora B kinase and Kif4A chromokinesin on chromosome arms. J Cell Biol. 2017 10 02; 216(10):3117-3132.
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Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation. J Cell Biol. 2012 10 15; 199(2):251-68.
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Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis. Science. 2010 10 08; 330(6001):231-5.
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Dietary flavonoid fisetin induces a forced exit from mitosis by targeting the mitotic spindle checkpoint. Carcinogenesis. 2009 Jun; 30(6):1032-40.
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ICIS and Aurora B coregulate the microtubule depolymerase Kif2a. Curr Biol. 2009 May 12; 19(9):758-63.
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Shugoshin 1 plays a central role in kinetochore assembly and is required for kinetochore targeting of Plk1. Cell Cycle. 2007 Jul 01; 6(13):1579-85.
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Survivin dynamics increases at centromeres during G2/M phase transition and is regulated by microtubule-attachment and Aurora B kinase activity. J Cell Sci. 2004 Aug 15; 117(Pt 18):4033-42.
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Mitosis: MCAK under the aura of Aurora B. Curr Biol. 2004 May 04; 14(9):R346-8.