Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome
"Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly evolutionarily conserved subunit of the anaphase-promoting complex (APC-C) containing multiple 34-amino-acid tetratricopeptide repeats. These domains, also found in Apc subunits 6, 7, and 8, have been shown to mediate protein-protein interactions, suggesting that Apc3 may assist in coordinating the juxtaposition of the catalytic and substrate recognition module subunits relative to co-activators and APC-C inhibitors.
| Descriptor ID |
D064191
|
| MeSH Number(s) |
D08.811.464.938.750.092.875 D12.776.167.024.875
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome".
Below are MeSH descriptors whose meaning is more specific than "Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome".
This graph shows the total number of publications written about "Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome" by people in this website by year, and whether "Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
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Below are the most recent publications written about "Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome" by people in Profiles.
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The dephosphorylated form of the anaphase-promoting complex protein Cdc27/Apc3 concentrates on kinetochores and chromosome arms in mitosis. Cell Cycle. 2002 Jul-Aug; 1(4):282-92.
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Distinct subunit functions and cell cycle regulated phosphorylation of 20S APC/cyclosome required for anaphase in fission yeast. J Cell Sci. 1997 Aug; 110 ( Pt 15):1793-804.