"Cdc20 Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly conserved proteins that specifically bind to and activate the anaphase-promoting complex-cyclosome, promoting ubiquitination and proteolysis of cell-cycle-regulatory proteins. Cdc20 is essential for anaphase-promoting complex activity, initiation of anaphase, and cyclin proteolysis during mitosis.
| Descriptor ID |
D064199
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| MeSH Number(s) |
D08.811.464.938.750.092.998 D12.776.167.024.998
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cdc20 Proteins".
Below are MeSH descriptors whose meaning is more specific than "Cdc20 Proteins".
This graph shows the total number of publications written about "Cdc20 Proteins" by people in this website by year, and whether "Cdc20 Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cdc20 Proteins" by people in Profiles.
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Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores. Curr Biol. 2005 Jun 21; 15(12):1078-89.
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Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells. J Cell Biol. 2002 Sep 02; 158(5):841-7.
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The dephosphorylated form of the anaphase-promoting complex protein Cdc27/Apc3 concentrates on kinetochores and chromosome arms in mitosis. Cell Cycle. 2002 Jul-Aug; 1(4):282-92.
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Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events. J Cell Biol. 1998 Jun 15; 141(6):1393-406.